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The RAC 3-Pillar Trifecta, page-177

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    It needs a target occupancy study where the drug in various doses has a radioactive tracer attached and then do a brain scan.

    That would determine the minimum dose to reach all parts of the brain.

    Safety is already known.

    Then a small P2 PoC.

    Then the RAC phone lines will melt down.
 
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