Here you go again....
There is more scientific research methodology and data in this one definitive paper than the hole anti-vaxx conspiracy network 10 times over.paper athttp://www.sciencedirect.com/science/article/pii/S0264410X14006367Go on read it. Do some research for once -- or at least try and understand how to do it properly.Contains....1,500,000 data points ( thats one million five hundred thousand observations)Proves.....Found there was no connection between vaccination and autism.• There wasno relationshipbetween vaccination and autism (OR: 0.99; 95% CI: 0.92 to 1.06).• There wasno relationshipbetween vaccination and ASD (autism spectrum disorder) (OR: 0.91; 95% CI: 0.68 to 1.20).• There wasno relationshipbetween [autism/ASD] and MMR (OR: 0.84; 95% CI: 0.70 to 1.01).• There wasno relationshipbetween [autism/ASD] and thimerosal (OR: 1.00; 95% CI: 0.77 to 1.31).• There wasno relationshipbetween [autism/ASD] and mercury (Hg) (OR: 1.00; 95% CI: 0.93 to 1.07).• Findings of this meta-analysis suggest that vaccinations arenot associatedwith the development of autism or autism spectrum disorder.paper athttp://www.sciencedirect.com/science/article/pii/S0264410X14006367https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057555/Background
Whether unvaccinated children and adolescents differ from those vaccinated in terms of health is subject to some discussion.
Method
We evaluated data on diseases that are preventable by vaccination, infectious and atopic diseases, and vaccinations received that had been collected between 2003 and 2006 in a representative sample of 17 641 subjects aged 0 to 17 years in the framework of the German Health Interview and Examination Survey for Children and Adolescents (Kinder- und Jugendgesundheitssurvey, KiGGS).
Results
Evaluable data on vaccinations were available for 13 453 subjects aged 1–17 years from non-immigrant families. 0.7% of them (95% confidence interval: 0.5%–0.9%) were not vaccinated. The lifetime prevalence of diseases preventable by vaccination was markedly higher in unvaccinated than in vaccinated subjects. Unvaccinated children aged 1–5 years had a median number of 3.3 (2.1–4.6) infectious diseases in the past year, compared to 4.2 (4.1–4.4) in vaccinated children. Among 11- to 17-year-olds, the corresponding figures were 1.9 (1.0–2.8) (unvaccinated) versus 2.2 (2.1–2.3) (vaccinated). The lifetime prevalence of at least one atopic disease among 1- to 5-year-olds was 12.6% (5.0%–28.3%) in unvaccinated children and 15.0% (13.6%–16.4%) in vaccinated children. In older children, atopy was more common, but its prevalence was not found to depend on vaccination status: among 6- to 10-year-olds, the prevalence figures were 30.1% (12.9%–55.8%) for unvaccinated children versus 24.4% (22.8%–26.0%) for vaccinated children, and the corresponding figures for 11- to 17-year-olds were 20.3% (10.1%–36.6%) versus 29.9% (28.4%–31.5%).
Yes another study which you say hasn't happened.....
https://www.tandfonline.com/doi/abs/10.1080/00036846.2011.566203#.VM4Ni2TF8oWe use data from the Cebu Longitudinal Health and Nutrition Survey (CLHNS) in the Philippines to link vaccination in the first 2 years of life with later physical and cognitive development in children. We use propensity score matching to estimate the causal effect of vaccination on child development. We find no effect of vaccination on later height or weight, but full childhood vaccination for measles, polio, Tuberculosis (TB), Diphtheria, Pertussis and Tetanus (DPT) significantly increases cognitive test scores relative to matched children who received no vaccinations.The size of the effect is large, raising test scores, on average, by about half an SD.Gee, here's anothe onehttps://www.ncbi.nlm.nih.gov/pubmed/2260220Vaccinated versus unvaccinated children: how they fare in first five years of life.
Abstract
Twenty five children who had undergone their full course of childhood immunization schedule were compared with 25 children who did not have any vaccinations for a period of five years. Parameters for comparison were measles, pertussis, poliomyelitis, tetanus and tuberculosis. Out of the 25 vaccinated children, only one child had mild measles at 2 1/2 years while 4 had suspected whooping cough at different points of the study period but not clinically diagnosed as pertussis. Among the unvaccinated group, 2 died of measles before the age of 3 years while 11 others went down with measles during an outbreak in 1986. An unvaccinated child also died of tetanus within the study period. In this paper we advocate the total integration of every community in the ongoing Expanded Programme for Immunization in Nigeria.
Influenza causes significant morbidity and mortality (1–3). Effectiveness of the vaccine and severity of the clinical manifestations of infection are highly variable each year. The rate of influenza vaccination in the United States has increased in recent years but remains poor (4,5). We have previously reported our experience in the intensive care unit (ICU) with influenza A, H1N1 pandemic 2009 virus (pH1N1) (6,7). We now report our initial observations for the 2013–2014 influenza season. We observe a very high number of otherwise healthy individuals with critical illness requiring care in the ICU. Most patients who required ICU level care were not previously vaccinated.
To determine whether patients requiring ICU care have a lower rate of vaccination prior to hospitalization, we reviewed the records of all hospitalized patients who tested positive for the influenza virus by polymerase chain reaction assay at our institution between November 1, 2013, and January 8, 2014. Basic patient demographics and underlying risk factors for severe influenza are provided (Table 1). The median age in our cohort was 28.5 years (range: 2 mo to 101 yr), similar to the age distribution observed during the 2009–2010 influenza season (8).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175560/In an effort to overcome these limitations, we digitized all weekly surveillance reports of notifiable diseases for U.S. cities and states published between 1888 and 2011. This data set, which we have made publicly available (www.tycho.pitt.edu), consists of87,950,807 reported individual cases, each localized in space and time.We used these data to derive a quantitative history of disease reduction in the United States over the past century, focusing particularly on the effect of vaccination programs.
We obtained all weekly notifiable disease surveillance tables published between 1888 and 2011 in theMorbidity Mortality Weekly Reportand its precursor journals from various online and hardcopy sources.21–24We digitized all data available in tabular format that listed etiologically defined cases or deaths by week for locations in the United States. Reported counts (weekly tallies) of cases or deaths and the reporting locations, periods, and diseases were extracted from these data and standardized. Then we selected eight vaccine-preventable contagious diseases for more detailed analysis and computed weekly incidence rates, deriving a quantitative history of each disease.
https://www.jacionline.org/article/S0091-6749(13)01860-5/abstractBackground
The lack of longitudinal data analyses from birth to adulthood is hampering long-term asthma prevention strategies.
Objective
We aimed to determine early-life predictors of asthma incidence up to age 20 years in a birth cohort study by applying time-to-event analysis.
Methods
In 1990, the Multicenter Allergy Study included 1314 newborns in 5 German cities. Children were evaluated from birth to age 20 years at 19 time points. Using a Cox regression model, we examined the associations between 36 early-life factors and onset of asthma based on a doctor's diagnosis or asthma medication (primary outcome), typical asthma symptoms, or allergic asthma (including positive IgE measurements).
Results
Response at 20 years was 71.6%. Two hundred eighteen subjects met the primary outcome criteria within 16,257 person years observed. Asthma incidence was lower in participants who were vaccinated (measles, mumps, and rubella vaccine/tick-borne encephalitis vaccine/BCG vaccine: adjusted hazard ratio [HR], 0.66 [95% CI, 0.47-0.93]). Up to age 20 years, asthma incidence was higher in subjects who had parents with allergic rhinitis (adjusted HR, 2.24 [95% CI, 1.67-3.02]), started day care early or late (before 18 months: adjusted HR, 1.79 [95% CI, 1.03-3.10]; after 3 years: adjusted HR, 1.64 [95% CI, 0.96-2.79]), had mothers who smoked during pregnancy (adjusted HR, 1.79 [95% CI, 1.20-2.67]), had poor parents (adjusted HR, 1.55 [95% CI, 1.09-2.22]), and had parents with asthma (adjusted HR, 1.65 [95% CI, 1.17-2.31]). Not associated with asthma were aspects of diet and breast-feeding, pet ownership, presence of older siblings, and passive smoking.
Conclusion
Parental asthma and nasal allergy increase asthma incidence in offspring up to adulthood. Avoiding tobacco smoke exposure during pregnancy, receiving vaccinations in early childhood, and starting day care between 1.5 and 3 years of age might prevent or delay the development of asthma.
Vaccine-Preventable Diseases
The past decade has seen substantial declines in cases, hospitalizations, deaths, and health-care costs associated with vaccine-preventable diseases. New vaccines (i.e., rotavirus, quadrivalent meningococcal conjugate, herpes zoster, pneumococcal conjugate, and human papillomavirus vaccines, as well as tetanus, diphtheria, and acellular pertussis vaccine for adults and adolescents) were introduced, bringing to 17 the number of diseases targeted by U.S. immunization policy. A recent economic analysis indicated that vaccination of each U.S. birth cohort with the current childhood immunization schedule prevents approximately 42,000 deaths and 20 million cases of disease, with net savings of nearly $14 billion in direct costs and $69 billion in total societal costs.2
The impact of two vaccines has been particularly striking. Following the introduction of pneumococcal conjugate vaccine, an estimated 211,000 serious pneumococcal infections and 13,000 deaths were prevented during 2000-2008.3Routine rotavirus vaccination, implemented in 2006, now prevents an estimated 40,000-60,000 rotavirus hospitalizations each year.4Advances also were made in the use of older vaccines, with reported cases of hepatitis A, hepatitis B, and varicella at record lows by the end of the decade. Age-specific mortality (i.e., deaths per million population) from varicella for persons age <20 years, declined by 97% from 0.65 in the prevaccine period (1990-1994) to 0.02 during 2005-2007.5Average age-adjusted mortality (deaths per million population) from hepatitis A also declined significantly, from 0.38 in the prevaccine period (1990-1995) to 0.26 during 2000-2004.6
It's all there....can you read?You are wasting your time MentaYou are wasting your life Menta
