There is a new study about aluminium and familial alzheimer’s disease.
https://content.iospress.com/articles/journal-of-alzheimers-disease/jad191140
"DISCUSSION
The aluminum content of brain tissue from donors with the PS1-E280A fAD mutation was universally high with 42% of tissues having a concentration of aluminum above 3.00 μg/g dry wt., a content considered as pathologically significant [10]. Aluminum content in brain tissue in fAD was significantly higher than brain tissues from donors with neither clinical nor neuropathological diagnosis of neurodegenerative disease (Exley and Clarkson, unpublished). The new data confirm unequivocally the previous observation of very high brain aluminum content in fAD"
"This is the second study confirming significantly high brain aluminum content in fAD but it is the first to demonstrate an unequivocal association between the location of aluminum and amyloid-β in fAD. It shows that two prominent risk factors in the etiology of AD [15, 16] are intimately interwoven in the neuropathology of fAD. While there is a long history suggesting a role for aluminum in the provenance of senile plaques [17], the observation herein of the co-localization of aluminum and amyloid-β in vasculature has not previously been seen in either cerebral amyloid angiopathy [18] or autism spectrum disorder (Mold and Exley, unpublished)."
