re: obj - backing a winner Transdermal or through the skin application was probably the very first drug delivery method. Our ancestors applied leaves, juice, bark and sap to their skin to treat a range of conditions and injuries. Transdermal patches, gels and creams may be the modern equivalent, however, the obstacle, the skin’s barrier effect, remains the same.
The human skin is exquisitely effective at keeping all but the smallest and simplest of compounds out. The stratum corneum, the protective barrier of the skin’s outer layers, ensures that we do not swell up in the shower, absorb dangerous chemicals we may touch, or allow even the tiniest of bacteria to enter through the skin.
To avoid the molecular limits that nature places on traditional transdermal drug delivery, Dermaportation adopts an active role by using energy to temporarily affect drug transport through the skin.
As a result, Dermaportation is better positioned to meet the changing delivery needs of existing drugs as well as those of the new biological drugs, emerging from global investments in automated drug discovery and genome projects
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