Tiresiias: "Back to the Future", page-3

A very recent literature review.
Confocal Laser Microscopy in Neurosurgery: State of the Art of Actual Clinical Applications
DOI:10.3390/jcm10092035

positive
Confocal imaging may be used to check for the presence of tumor at the tumor margins, possibly increasing EOR.

negatives
Extremely large quantities of data for the surgeon to analyse live and .
"Often, it is not feasible to image the entire resection cavity due to the small field of view of the CLE although there is no practical necessity to screen the entire surgical bed, given that the rationale of using this technology is to acquire “optical biopsies” in selected regions".

Conclusion

it is reasonable to suppose that further studies may elucidate whether subsequent routine use of CLE-assisted surgery may significantly improve both the diagnosis and the treatment of tumorous processes, offering patients an increased survival rate and quality of life.