today tonight!!!!, page-27

I doubt Doogs you will find specific answers to your questions as NB and Rebel are saying. But from little dribs and drabs of the pilot studies from Wright et al., around the place – that I think relate to the current formulation of Thermalife you get:

An effective dose is:
Normally an effective dose will be found in the range of about 1 to about 6 mg/kg body weight. For an average 75 kg subject, this range equates to a dose of about 75 to about 450 mg. Such a dose can be administered as needed, but typically administration 1 to about 4 times per day, in most cases 1 or 2 times a day, provides adequate continuing relief of pain.

Who does it work for:
It was observed that in the more chronic situation, elderly, local arthritis (in particular osteo-arthritis), results were more predictable. Clinically, it appears that local application of the topical analgesic agent to a pathological joint produces some effect.

Of the small numbers used in this trial, the best results were obtained with patients having single joint pain or relatively localized nonjoint pain. Patients whose general health was reasonable was more important than the age of patient. Finally, non-weight bearing joints responded more quickly than weight bearing joints.

The best results were obtained where local rather than vague general pain was evident. Repetitive strain injury was not helped by the use of the analgesic unless the condition was of the very local category--eg. Tennis elbow. Conversely, with the "arthritic" Group B pain from osteo-arthritis was definitely reduced whilst the analgesic was being used. However, following cessation of treatment in may instance, the pain gradually returned.

This of-course is very anecdotal but that is the nature of the beast here.