A vaccine is any preparation intended to produce immunity to a disease by stimulating the production of antibodies. Vaccines include, for example, suspensions of killed or attenuated microorganisms, or products or derivatives of microorganisms. The most common method of administering vaccines is by injection. We see the rapid development of a trandermal vaccine device to eliminate the need for hypodermic needles.
The World Health Organisation (W.H.O.) has estimated that needle reuse causes the deaths of at least 1.3 million people per year from hepatitis B and AIDS.??Needle-free, patch-based vaccination?will have a large impact.? In addition, the possibility of administering vaccine patches by poorly trained personnel or patients themselves could not only facilitate compliance with routine, seasonal and pandemic vaccination needs, but also expedite vaccination campaigns in third world and developing countries where medical?professionals are in short supply.
New vaccines also have been introduced with significant results, including the first vaccine to help prevent liver cancer, hepatitis B vaccine, which is now routinely given to infants in 77% of WHO member States. Rapid progress in the development of new vaccines means protection will be available in the near future against a wider range of serious infectious diseases.
Immupatch?
The delivery of a vaccine by a transdermal patch will revolutionise?immunisation in third world and developing counties. You could develop the best vaccine in the world, but if it can?t get to the people who need it, it?s hardly worth having. An easy-to-use patch that sticks on to your skin and delivers a vaccine immediately can offer many benefits. The patch will be easier to ship, store and use than the conventional needle, syringe and vial, and this is particularly important in regions with limited access to clinical facilities, such as remote areas or parts of the developing world.
To administer, the patch is simply placed directly on the skin, then peeled off and discarded.? Trials being conducted in Europe, USA, Asia and Australia, show the transdermal technology when applied with vaccine delivery can be more effective at generating an immune response to a commercial vaccine when compared with a needle and syringe delivery, and unlike the major competitor product, the patch requires no vaccine adjuvant and can be administered in a single step.??
Calm-patch? Attention-Deficit Hyperactivity Disorder (ADHD or AD/HD) is a neurobehavioral developmental disorder. ADHD is primarily characterized by the co-existence of attentional problems and hyperactivity, with each behaviour occurring infrequently alone. ADHD management usually involves some combination of medications, behaviour modifications, lifestyle changes, and counselling.?
Whilst a well known patch has been available in the US for period of time it has been the subject of many recalls,?our vision is for a collaborating partner to bring?to market a reliable transderaml patch under our brand?for use in this area. A patch is preferable in cases where substance abuse is an issue, as a patch cannot easily be tampered with, but can still be distributed.
Lifepatch?
Various?transdermal patches are available to treat different types of depressions. Major depressive episodes (DSM-IV) imply a prominent and relatively persistent (nearly every day for at least 2 weeks) depressed or dysphoric mood that usually interferes with daily functioning, and includes at least five of the following nine symptoms: depressed mood, loss of interest in usual activities, significant change in weight and/or appetite, insomnia or hypersomnia, psychomotor agitation or retardation, increased fatigue, feelings of guilt or worthlessness, slowed thinking or impaired concentration, and suicide attempt or suicidal ideation.**
We aim to work with our collaborative partners to commercial a suite of products?that will assist in normalising the life of these episodic events, by allowing transdermal science to provide a sustained release pharmaceuticals. Many individuals with these life problems resist taking oral formulations as they believe they no longer need them.?Lifepatch? will assist individuals and families across the globe on a ?Daily basis.
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