That's right. Unless any new results are remarkable, the phase 2A and 2B studies both raise questions that I think the FDA will want addressed i.e. why does the 0.07 dose work but not the 0.15 dose etc.
LOR also does not appear to act as a DMOAD, since no significant difference in medial joint space width was observed between between LOR and PBO groups after 18 months of follow up.
I also wonder whether the FDA would request confirmatory trials to be conducted by an independent CRO.
I'm not convinced the current set of trials are enough to receive registration for LOR, unlike for PAR, since PAR's set of clinical trials are a lot more comprehensive.
Biosplice are taking quite the gamble looking at NRS pain reduction at 12 weeks as their primary endpoint in the P3 trials.
- Forums
- ASX - By Stock
- Trial PAR008 is on ANZCTR
That's right. Unless any new results are remarkable, the phase...
-
- There are more pages in this discussion • 1 more message in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add PAR (ASX) to my watchlist
|
|||||
Last
23.0¢ |
Change
0.010(4.55%) |
Mkt cap ! $80.45M |
Open | High | Low | Value | Volume |
22.8¢ | 23.3¢ | 22.5¢ | $46.92K | 203.9K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
1 | 337 | 23.0¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
23.5¢ | 138166 | 5 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
1 | 337 | 0.230 |
5 | 91706 | 0.225 |
15 | 184871 | 0.220 |
6 | 73458 | 0.215 |
6 | 146050 | 0.210 |
Price($) | Vol. | No. |
---|---|---|
0.235 | 138166 | 5 |
0.250 | 15000 | 1 |
0.260 | 26050 | 3 |
0.270 | 13000 | 2 |
0.275 | 10000 | 1 |
Last trade - 16.10pm 16/08/2024 (20 minute delay) ? |
Featured News
PAR (ASX) Chart |