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Looks like its related to a posting on the Cellmid facebook timeline, seems to be not directly related to Cellmid although please correct me if I'm wrong. Appears to be Cellmid keeping us informed of items of interest in the immuno-oncology field. Extract from the referenced article below..........


Aduro BioTech joined the short list companies outside Big Pharma to pick up the FDA's coveted breakthrough therapy designation, impressing the agency with strong mid-stage results for its combo cancer therapy.
An FDA breakthrough tag entitles Aduro to a speedy review and access to senior agency staff as it works through the regulatory process with CRS-207 and GVAX, two immunotherapies designed to battle pancreatic cancer in tandem.
The regulatory victory comes on the heels of positive Phase II data for the combination, in which Aduro's cocktail beat out GVAX alone in 93 patients with metastatic pancreatic cancer. Median overall survival on the combo came in at 6.1 months, a statistically significant improvement over GVAX's 3.9 months.
Now Aduro is working through an expanded Phase IIb trial, enrolling about 240 patients into three treatment arms: one receiving the combination treatment, one taking CRS-207 alone and another on standard chemotherapy. The study's primary endpoint is overall survival, and Aduro hopes it'll back up the safety, immune response and efficacy CRS-207 and GVAX have demonstrated thus far.
The biotech expects to complete enrollment in that trial by the end of next year with an estimated completion date of December 2016. And with the FDA's promise of special attention, Aduro is optimistic about the future for its oncology combo, CEO Stephen Isaacs said.
"This designation underscores the potential of our combination immunotherapy approach to make a difference in the lives of patients with pancreatic cancer, which remains a very difficult cancer to treat," Isaacs said in a statement.