...Dr Heinrich says much work is needed before they can be used to treat humans, as developing peptides as drugs is challenging because they are small, relatively expensive and easily filtered out of the body.
Their best application may be niche areas like catheter linings and burns wounds where patients develop multi-drug resistance infections because they spend months on antibiotics.
“In this instance you could spray them onto a wound and the issue of the peptides being easily flushed out by kidneys wouldn’t be an issue any more,” Dr Heinrich says.
I would assume that the same issues would come up for oncology drugs, too, although likely to be less sensitive to expense. And it sounds like they've made some progress with serum stability with proprietary myc inhibitors.
Exee
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