Upcoming Cancer Clinical Trials To Begin INV043

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    Some good news regarding Clinical Trials

    R&D activities during the quarter June 2023

    Invion is developing the Photosoft™ technology for the treatment of cancers and infectious
    diseases and atherosclerosis (AID).

    The Company’s priority during the quarter is to work with its partners, including the Peter
    MacCallum Cancer Centre and Hudson Institute of Medical Research, to complete the
    preparatory groundwork for the upcoming clinical trials. The drug discovery work on both
    topical and intravenous (IV) formulations of INV043, the lead drug candidate, have been
    completed.

    Meanwhile, Invion and its partners have made significant progress on the pre-clinical studies
    required for the Phase 1trials, including having largely completed this work for the topical drug
    product, which will be used in the skin cancer and anogenital cancer trials.

    The Company is progressing on the pre-clinical studies for the IV drug product that will be used
    in future solid tumour clinical trials.

    Further, Invion is working with IDT Australia Limited (ASX: IDT) on manufacturing the Active
    Pharmaceutical Ingredient (API) drug substance, and is also working on manufacturing drug
    products for both topical and IV administrations.

    Additionally, drug discovery studies using Photosoft on infectious diseases and atherosclerosis
    are continuing with research partners including the Australian Centre for Antimicrobial
    Resistance Ecology (ACARE), which is part of the University of Adelaide. Invion will release
    further results from these studies as they become available.
 
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