I think their CORE-NK platform will be their most successful program especially once they integrate the CDH-17 and CLTX biomarkers. It will be allogeneic and can produce the same efficacy rates as CAR-T programs. However, it is still a mystery whether they will work in solid tumours. Crossing into the tumour microenvironment will always be an issue and dealing with tumor evasion due to the variety of biomarkers may affect durability and metastases so we'll see.
They are targetting hematological tumours so you may see the same efficacy rates that we've seen from Nkarta and Fate therapeutics' CAR-NK programs.
I think their CORE-NK platform will be their most successful...
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