PYC has filed another patent for treatment of kidney disease on...

PYC has filed another patent for treatment of kidney disease on 16.06.2023!

Types of hereditary kidney diseases

The most common hereditary kidney disease is autosomal dominant polycystic kidney disease (ADPKD). People with ADPKD form cysts on their kidneys. The cysts fill with fluid and damage their kidneys over time. Doctors can diagnose ADPKD before the age of 40, at a time kidney function measurement appears normal. But, it's crucial not to wait until the kidney function begins to decline to seek advice about ADPKD.

Early treatment can delay the progression of the disease by many years. Plus, people with ADPKD can have kidney infections, kidney stones, and blood in their urine for reasons that are different than others.

A few other common hereditary kidney disorders include:

• Alport syndromeaffects between 30,000 and 60,000 people in the U.S. and causes blood and protein loss in the urine. Over time, it also causes kidney failure. It usually occurs in teenagers or young adults, but can happen at an older age.
• Cystinosiscauses damage to cells in the kidney, leading to Fanconi's syndrome. People with this syndrome lose excess electrolytes and amino acids in the urine.
• Fabry's diseasecauses kidney disease that can be hard to diagnose. People with Fabry's disease often have heart disease, visual problems, burning sensation of the skin, and possibly a decreased ability to sweat. Early diagnosis and treatment are vital.
• Thin basement membrane diseaseaffects less than 1% of people in the U.S. It results in blood in the urine that doctors can only diagnose by kidney biopsy.
• Barter's syndromeis a group of rare diseases that causes excess loss of sodium, acid, potassium, calcium, and magnesium in the urine. Gitleman syndrome is a related disorder that causes excess loss of the same ions — except calcium — in the urine.
• Focal and segmental glomerulosclerosis (FSGS)leads to loss of protein from the blood into the urine. It can lead to nephrotic syndrome, with severe swelling of the body and malnutrition. FSGS has both hereditary and non-hereditary causes, which doctors treat differently.

Congenital abnormalities of the kidney and ureteral tract (CAKUT) are a group of disorders that cause you to have either:

• Only one kidney.
• A small kidney.
• A mal-positioned kidney.
• Changes in how urine from the kidneys drain into the bladder.

Doctors most often diagnose CAKUT during childhood, but in some infants the disease doesn't show up. When CAKUT affects adults, they either have a single kidney or chronic kidney disease of unknown cause.

PYC is no longer an one-trick pony. With 1 drug in human trial, 2 in the pipeline for IND next year, 1 of which a CNS drug, now a kidney drug is about to be added to the pipeline, regardless of the current suppressed SP, I reckon it's a super overweight BUY! DYOR.

More information https://www.upmc.com/services/kidney-disease/conditions/inherited-kidney-disease#