We should have early readouts on whether the treatment is efficacious in 2 months time. Though I don't expect that this will be sufficient time for the altered T-Cells and HSC to multiply enough to call it a cure for HIV. We should know however, whether the drug is doing what it is supposed to be doing.
Busulfan is used as a pre-conditioning agent in the 2nd and 3rd cohorts, but may be unnessessary. The dose of Cal-1 does not change.
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