BOT botanix pharmaceuticals ltd

What's the vehicle anyhow?

  1. 1,400 Posts.
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    Does anyone know if the stuff that makes up Permetrex - the vehicle - can be effective on p-acne by itself and/or if (due to pour QA) when its formulation is partially changed so is its effect?

    From Botanix's patent application:

    Definitions: CBD: cannabidiol,
    IPA: isopropyl alcohol,
    HDS: hexylmethyldisiloxane,
    PG: propylene glycol,
    OA: oleyl alcohol,


    • 5%CBD/
    10%OA/10%PG/
    10%HDS/
    65%IPA


    Claims
    A pharmaceutical composition comprising a cannabinoid and a siloxane wherein the cannabinoid is dissolved in the composition.The pharmaceutical composition according to claim 1 wherein the cannabinoid is cannabidiol.The pharmaceutical composition according to claim 1 or 2 wherein the composition is for topical application.
    The pharmaceutical composition according to any one of the preceding claims wherein the siloxane: a) contains 2 or 3 silicon atoms; b) has a level of volatility about the same as that of isopropyl alcohol; and/or c) is selected from the group consisting of: hexamethyldisiloxane, octamethyltrisiloxane and combinations thereof.
    It couldn't be the vehicle, could it?
    Any thoughts? (apart from those the company has been put forward)

    https://patents.google.com/patent/WO2018148786A1/en
    Last edited by aburbe: 29/10/19
 
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