Now to introduce more fog.
ii) The issue includes the 5% BID US arm that performed as poorly as the Australian vehicle (26%)
iii) Manufacturing as an excuse has gone quiet - They should have verified the chemical compounds in the batches by now. Manufacturing must explain both a vehicle that performs highest in the study, and the strongest dose of active on the US study that performs like the AU vehicle.
iv) talking about non-inflam data is grasping at straws, being unable to explain the primary end point discrepancies in the US Vehicle (and US 5% BID).
What's the vehicle anyhow?, page-99
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