When mockers will thurst, page-4

2 Timothy 2:23
Don't have anything to do with foolish and stupid arguments, because you know they produce quarrels.

Barnes' Notes on the Bible

But foolish and unlearned questions avoid; - see the notes at 2 Timothy 2:16; compare the notes at 1 Timothy 1:4, 1 Timothy 1:6; 1 Timothy 4:7. The word "unlearned," here, means "trifling; that which does not tend to edification; stupid." The Greeks and the Hebrews were greatly given to controversies of various kinds, and many of the questions discussed pertained to points which could not be settled, or which, if settled, were of no importance. Such has been the character of no small part of the disputes which have agitated the world. Paul correctly says that the only effect of such disputes is to engender harsh contention. Points of real importance can be discussed with no injury to the temper; but people cannot safely dispute about trifles.

Ellicott's Commentary for English Readers

(23) But foolish and unlearned questions avoid.—The Greek word translated “unlearned” is better rendered ignorant. These “questions” which, as we have seen above, the false teachers, with whom Timothy was so much thrown, loved to put forward for discussion, could hardly be termed “unlearned”—much useless learning being often thrown away in these disputing of the schools—but were rather “pointless,” “stupid,” as well as foolish. The nature of these questions of controversy has been discussed above.

Knowing that they do gender strifes.—Knowing—as thou dost—from sad and frequent experience, what conflicts, heart-burnings, estrangements, these abstract questions between rival teachers and rival sects engendered.