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Where others have failed will Atl1102 succeed ?, page-741

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    Yes, and another rival going down the 'dystrophin' route.

    ...and targeting a small subset of DMD boys (13%)...same as Sarepta's Exondys51.

    PepGen stated goal is to raise 'wild-type dystrophin' to between 10-12%.

    BUT we know from Sraepta's results that:

    ...the additional dystrophin does not stop inflammation...in fact it may increase 'matrix deposition' / fibrosis as the body responds to the new 'wild-type' dystrophin.

    Biggest take away from me is the $113m CR...lots of Biotech $$$ looking for projects.

    Big week ahead folks!

    .
 
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