Hoyland is probably the best to answer your questions. However, here are a few links to nibble on to help with some o your latter questions and maybe help point you in the right direction.☺️
http://ddrnai.blogspot.com.au/2014/06/dr-peter-french-reply-to-dr-kss-article.html?m=1
http://m.seekingalpha.com/instablog...783-ttminus-034-safety-should-we-be-concerned
http://m.seekingalpha.com/instablog...26543-asgct-papers-point-to-success-of-ddrnai
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