There have been many many trials with those numbers in the past decade. Let me come back to later with details, as I am working today.
As to your second point, with all due respect to Big Pharma last time I checked things needed to be sold to someone, very few things are actually bought. Its up to the owner of IP to present a value proposition, as Seagen did recently. It rarely occurs the other way around..
There have been many many trials with those numbers in the past...
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