Im not sure how you have come up with .. "quite a portion of this particular Trial really had no benefit at all over SOC".
The HR confidence interval is asymmetric and this is because the HR itself is non-normal. ie not a symmetric bell curve. Why does this matter? It matters because it indicates the HR has quite a heavy right skewed distribution and this indicates that the upper tail of the distribution reaching out to the upper confidence interval is long AND therefore a large majority (than you are thinking) of the values in the distribution are actually closer to the mean HR value of 0.418.
Im not sure how you have come up with .. "quite a portion of...
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