I believe that is a foregone conclusion. After all, the whole point of PH1 is to determine tolerability and safety. If at highest dose, there is no tolerability and safety issue, then they would proceed with the highest dose.
Mind you, in PH1b, it is going to be a combo PD1-Vaxx/Tecentriq trial. So they might actually try that out with all the different doses or just the highest dose. I believe it depends on the data from PH1a and Tecentriq. I am sure the scientists will work out the dosage to use. Which is why LC has brought in the recent experts from Roche/Genentech to help out.
All will be revealed in time.
Why IMU is a multi multi bagger, page-5076
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