It cannot be understated how large the potential for this vaccine is:
High-risk HPV infection accounts for approximately 5 percent of all cancers worldwide (see links)
Almost every individual in the world will be exposed to a form of the virus in their lifetime - potential pool of vaccine candidates? EVERYONE!
http://www.cancer.gov/cancertopics/factsheet/Risk/HPV
In addition to those listed in the link above, even skin cancer has been linked to HPV infection:
http://www.livescience.com/36225-skin-cancer-risk-hpv.html
Fraser has an enviable track record when it comes to creating successful vaccines and this is a logical extension of his previous work = a very high probability for success.
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