http://www.zhxhwk.com/uploads/20162qk/20150578.pdf I leave for...

http://www.zhxhwk.com/uploads/20162qk/20150578.pdf

I leave for others to read and make some informed view. Interesting that is another paper out of China - does anyone know is BTG has a sales channel into China?

Ｒｅｓｅａｒｃｈ ｐｒｏｇｒｅｓｓ ｏｆ Ｙｔｔｒｉｕｍ ９０ ｉｎ ｔｈｅ ｔｒｅａｔｍｅｎｔ ｏｆ ｕｎｒｅ ｓｅｃｔａｂｌｅ ａｎｄ ｃｈｅｍｏｔｈｅｒａｐｙ ｔｏｌｅｒａｎｔ ｃｏｌｏｒｅｃｔａｌ ｌｉｖｅｒ ｍｅｔａｓｔａｓｉｓ Ｊｉａ Ｚｈｏｎｇｚｈｉ，Ｚｈｕ Ｃｈｕｎｆｕ，Ｑｉｎ Ｘｉｈｕ．Ｄｅｐａｒｔｍｅｎｔ ｏｆ Ｉｎｔｅｒｖｅｎｔｉｏｎａｌ Ｒａｄｉｏｌｏｇｙ，Ｎｏ．２Ｐｅｏｐｌｅ′ｓ Ｈｏｓｐｉｔａｌ ｏｆ Ｃｈａｎｇｚｈｏｕ， Ｎａｎｊｉｎｇ Ｍｅｄｉｃａ ｌＵｎｉｖｅｒｓｉｔｙ，Ｃｈａｎｇｚｈｏｕ２１３００３，Ｃｈｉｎａ Ｃｏｒｒｅｓｐｏｎｄｉｎｇ ａｕｔｈｏｒ：ＱｉｎＸｉｈｕ，Ｅｍａｉｌ：ｑｉｎｘｉｈｕ＠１２６．ｃｏｍ

【Ａｂｓｔｒａｃｔ】 Ｃｏｌｏｒｅｃｔａｌ ｌｉｖｅｒｍｅｔａｓｔａｓｉｓ（ＣＲＬＭ）ｉｓ ａ ｃｏｍｍｏｎ ｌｉｖｅｒ ｍｅｔａｓｔａｔｉｃ ｔｕｍｏｒ ｗｉｔｈ ｐｏｏｒ ｐｒｏｇｎｏｓｉｓ．Ｉｔ ｗａｓ ｖｅｒｙ ｄｉｆｆｉｃｕｌｔ ｔｏ ｔｒｅａｔｐａｔｉｅｎｔｓ ｗｉｔｈ ｕｎｒｅｓｅｃｔａｂｌｅ ａｎｄ ｃｈｅｍｏｔｈｅｒａｐｙ ｔｏｌｅｒａｎｔ ＣＲＬＭ．Ｗｉｔｈ ｔｈｅ ｔｕｍｏｒ ｃｏｎｔｒｏｌ ｒａｔｅｒａｎｇｉｎｇ ｆｒｏｍ６３％ ｔｏ ７８％，Ｙｔｔｒｉｕｍ ９０ ｉｓ ｂｏｔｈ ｓａｆｅ ａｎｄ ｅｆｆｅｃｔｉｖｅ ｉｎ ｔｒｅａｔｉｎｇ ｕｎｒｅｓｅｃｔ ａｂｌｅ ａｎｄ ｃｈｅｍｏｔｈｅｒａｐｙ ｔｏｌｅｒａｎｔ ＣＲＬＭ．Ｔｈｅ ｍｅｄｉａｎ ｓｕｒｖｉｖａｌ ｔｉｍｅ ｉｓ１０．５ｍｏｎｔｈｓ，ａｎｄ ｔｈｅ１，２，３ ｙｅａｒ ｏｖｅｒａｌｌ ｓｕｒｖｉｖａｌ ｒａｔｅｓ ｏｆ ｐａｔｉｅｎｔｓ ａｒｅ ４４％，２０％ ａｎｄ１４％ ｒｅｓｐｅｃｔｉｖｅｌｙ．Ｆｏｒ ａ ｃｅｒｔａｉｎ ｐｏｒｔｉｏｎ ｏｆ ｐａｔｉｅｎｔｓ，Ｙｔｔｒｉｕｍ ９０ ｈａｓ ｄｉｓｔｉｎｃｔ ａｄｖａｎｔａｇｅｓ ｏｖｅｒ ｍｏｌｅｃｕｌａｒ ｔａｒｇｅｔｅｄ ｄｒｕｇｓ ａｎｄ ｏｔｈｅｒ ｌｏｃａｌ ｍｉｎｉｍａｌｌｙ ｉｎｖａｓｉｖｅ ｔｒｅａｔｍｅｎｔ． Ｔｈｏｕｇｈ Ｙｔｔｒｉｕｍ ９０ ｔｒｅａｔｍｅｎｔ ｈａｓ ｓｈｏｗｅｄ ｃｅｒｔａｉｎ ｃｕｒａｔｉｖｅ ｅｆｆｅｃｔ，ｉｔｓ ｓａｆｅｔｙ ａｎｄ ｅｆｆｅｃｔｉｖｅｎｅｓｓ ｒｅｑｕｉｒｅ ｆｕｒｔｈｅｒ ｃｏｎｆｉｒｍａｔｉｏｎ ｔｈｒｏｕｇｈ ｍｕｌｔｉ ｃｅｎｔｅｒｒ ａｎｄ ｏｍｉｚｅｄ ｃｏｎｔｒｏｌｌｅｄ ｔｒｉａｌ．