ISOAY OTCQx.com BID/ASK spread is very large and much larger and...

ISOAY OTCQx.com BID/ASK spread is very large and much larger and ISN on the Australian Exchnnge.

I assume the marketmakers for ISOAY on the OTC would offer OR SUPPORT BID ASK approximately to the BID/ASK spread of ISN.
BID ASK
ISN .006 - .007

so my thinking is the ISOAY bid/ask should be around

ISOAY 3.00 4.20

I understood
500 ISN shares equals 1 ISOAY share

Currency conversion between US and Australian dollars is about 1:1 Not significant to consider for this approximation.

HOW ARE THESE THINGS SUPPOSE TO WORK?