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IMMUTEP LIMITED

Immutep Limited is an Australia-based clinical-stage biotechnology company. The Company... Immutep Limited is an Australia-based clinical-stage biotechnology company. The Company is focused on developing Lymphocyte Activation Gene (LAG)-3 immunotherapies for cancer and autoimmune diseases. Its lead product candidate, Eftilagimod alpha (efti or IMP321), is a soluble LAG-3Ig fusion protein that is an antigen-presenting cell (APC) agonist designed to capitalize on LAG-3’s ability to drive the adaptive and innate immune systems against cancer. IMP761 is an immunosuppressive agonist antibody to LAG-3, which has the potential to address the root cause of autoimmune diseases by specifically silencing autoimmune memory T cells. Its third product candidate is LAG525, an antagonist (blocking) antibody targeting the LAG-3 molecule on T cells with potential applications in the treatment of cancer. Its fourth product candidate is IMP731 (GSK 781), a depleting (cytotoxic) antibody that is intended to destroy LAG-3 expressing activated T cells involved in autoimmunity.More

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Timeline

Positive initial data in phase 2 Soft Tissue Sarcoma trial
02 May 09:29
 
Immutep Quarterly Activities Report and Appendix 4C
29 Apr 08:18
 
Positive preliminary topline results from TACTI-003 Cohort B
24 Apr 08:40
 
CHDR to conduct first-in-human phase 1 trial of IMP761
18 Apr 09:36
 
Positive Feedback received from Spanish Medicines Agency
17 Apr 09:10
 
Ceasing to be a substantial holder
11 Apr 18:30
 
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42.0¢ 43.0¢ 40.5¢ $1.108M 2.653M

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42.0¢ 101546 47
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