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PARADIGM BIOPHARMACEUTICALS LIMITED.. - Announcements

Paradigm Biopharmaceuticals Limited is a late-stage drug development company. The Company... Paradigm Biopharmaceuticals Limited is a late-stage drug development company. The Company is engaged in discovering, developing, and delivering pharmaceutical therapies. It is focused on the development of injectable pentosan polysulfate sodium (iPPS/PPS) for the treatment of osteoarthritis (OA) and mucopolysaccharidosis (MPS). Pentosan polysulfate sodium is a semi-synthetic drug manufactured from the wood chips of European beech trees. Extracted glucurono-xylans are sulfated to produce a negatively charged product that mimics glycosaminoglycans (GAGs). It develops PPS under the brand name Zilosul. PPS also inhibits the synthesis of the metalloproteinase, MMP-3 (Troeberg) involved in degrading cartilage. PPS also include treatment of joint function, mobility, and pain in patients with MPS; treating alphavirus-induced arthralgia (such as Ross River virus and Chikungunya); chronic heart failure (HF) and acute respiratory distress syndrome (ARDS).More

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PAR Change in substantial holding22/05/24 download Created with Sketch. 8.51MB
PAR Application for quotation of securities - PAR20/05/24 download Created with Sketch. 15.51KB
PAR Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE30/04/24 download Created with Sketch. 325KB
PAR Notification of cessation of securities - PAR26/04/24 download Created with Sketch. 13.22KB
PAR Type D Response Submitted and Received by the US FDAPRICE SENSITIVE19/04/24 download Created with Sketch. 157.42KB
PAR Notification of cessation of securities - PAR05/04/24 download Created with Sketch. 13.23KB
PAR PAR to present at NWR Healthcare Conference20/03/24 download Created with Sketch. 90.2KB
PAR Change of Director's Interest Notice08/03/24 download Created with Sketch. 169.7KB
PAR Change of Director's Interest Notice08/03/24 download Created with Sketch. 180.97KB
PAR Final Director's Interest Notice06/03/24 download Created with Sketch. 150.9KB
PAR Initial Director's Interest Notice04/03/24 download Created with Sketch. 157.18KB
PAR Paradigm Board Changes04/03/24 download Created with Sketch. 135.46KB
PAR Notification regarding unquoted securities - PAR29/02/24 download Created with Sketch. 16.25KB
PAR PAR Employee Performance Rights Plan Issue29/02/24 download Created with Sketch. 112.65KB
PAR Half Yearly Report and AccountsPRICE SENSITIVE28/02/24 download Created with Sketch. 3.77MB
PAR Notification regarding unquoted securities - PAR13/02/24 download Created with Sketch. 17.5KB
PAR Proposed issue of securities - PAR12/02/24 download Created with Sketch. 23.96KB
PAR PAR Appoints Business Development Consultant09/02/24 download Created with Sketch. 143.13KB
PAR Primary Endpoint Achieved in Phase 2 MPS VI TrialPRICE SENSITIVE09/02/24 download Created with Sketch. 387.82KB
PAR Paradigm Receives $7.36m R&D Tax Incentive RefundPRICE SENSITIVE07/02/24 download Created with Sketch. 61KB
PAR Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE31/01/24 download Created with Sketch. 350.17KB
PAR Notification of cessation of securities - PAR30/01/24 download Created with Sketch. 21.97KB
PAR Application for quotation of securities - PAR30/01/24 download Created with Sketch. 24.1KB
PAR PAR Selected for Major OA Conference Presentations30/01/24 download Created with Sketch. 127.74KB
PAR Notice of release of escrowed securities15/01/24 download Created with Sketch. 299.38KB
PAR Change in substantial holding06/12/23 download Created with Sketch. 225.29KB
PAR Change of Director's Interest Notice - Fisher01/12/23 download Created with Sketch. 175.33KB
PAR Change of Director's Interest Notice - Rennie30/11/23 download Created with Sketch. 181.58KB
PAR Notification of cessation of securities - PAR30/11/23 download Created with Sketch. 21.48KB
PAR Application for quotation of securities - PAR30/11/23 download Created with Sketch. 24.73KB
PAR Results of Meeting29/11/23 download Created with Sketch. 286.34KB
PAR 2023 AGM Company Update29/11/23 download Created with Sketch. 5.6MB
PAR 2023 AGM Chairman Address29/11/23 download Created with Sketch. 105.44KB
PAR Security Class Reinstatement to Quotation PAROPRICE SENSITIVE28/11/23 download Created with Sketch. 86.83KB
PAR Listing of Options - Top 20 Holders and Distribution Reports27/11/23 download Created with Sketch. 77.91KB
PAR Application for quotation of securities - PAR27/11/23 download Created with Sketch. 28.91KB
PAR Successful completion of Retail Entitlement OfferPRICE SENSITIVE23/11/23 download Created with Sketch. 138.29KB
PAR Security Class Suspension from Quotation PAROPRICE SENSITIVE21/11/23 download Created with Sketch. 89.1KB
PAR Application for quotation of securities - PAR20/11/23 download Created with Sketch. 24.13KB
PAR PAR Pre-AGM Update20/11/23 download Created with Sketch. 166.74KB
PAR Notice of release of escrowed securities10/11/23 download Created with Sketch. 295.15KB
PAR Application for quotation of securities - PAR08/11/23 download Created with Sketch. 26.91KB
PAR Retail Entitlement Offer Open06/11/23 download Created with Sketch. 128.5KB
PAR Addendum to Notice of Meeting03/11/23 download Created with Sketch. 693.49KB
PAR Paradigm to Recommence TradingPRICE SENSITIVE01/11/23 download Created with Sketch. 81.34KB
PAR Proposed issue of securities - PAR31/10/23 download Created with Sketch. 30.43KB
PAR Update - Proposed issue of securities - PAR31/10/23 download Created with Sketch. 48.67KB
PAR Replacement Entitlement Offer and Placement ProspectusPRICE SENSITIVE31/10/23 download Created with Sketch. 567.84KB
PAR PAR Successful Placement and Fully Underwritten ANREOPRICE SENSITIVE31/10/23 download Created with Sketch. 141.62KB
PAR Update - Proposed issue of securities - PAR30/10/23 download Created with Sketch. 46.32KB
PAR Entitlement Offer and Placement ProspectusPRICE SENSITIVE30/10/23 download Created with Sketch. 525.55KB
PAR Proposed issue of securities - PAR30/10/23 download Created with Sketch. 47.97KB
PAR Investor Presentation - $30m Capital RaisePRICE SENSITIVE30/10/23 download Created with Sketch. 10.88MB
PAR Paradigm Launches $30M Capital RaisingPRICE SENSITIVE30/10/23 download Created with Sketch. 166.04KB
PAR Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE30/10/23 download Created with Sketch. 302.47KB
PAR Trading HaltPRICE SENSITIVE30/10/23 download Created with Sketch. 274.36KB
PAR Notice of Annual General Meeting/Proxy Form25/10/23 download Created with Sketch. 467.1KB
PAR Final Director's Interest Notice23/10/23 download Created with Sketch. 150.44KB
PAR Resignation of Non-executive Director20/10/23 download Created with Sketch. 83.31KB
PAR iPPS Increases Cartilage Thickness in Phase 2 TrialPRICE SENSITIVE18/10/23 download Created with Sketch. 6.69MB
PAR Trading HaltPRICE SENSITIVE16/10/23 download Created with Sketch. 250.96KB
PAR iPPS SIGNIFICANT OA PAIN REDUCTION AT 12 MONTHSPRICE SENSITIVE10/10/23 download Created with Sketch. 7.37MB
PAR Trading HaltPRICE SENSITIVE06/10/23 download Created with Sketch. 259.19KB
PAR Date of AGM & Closing Date for Director Nominations03/10/23 download Created with Sketch. 83.54KB
PAR Change of Share Registry Details22/09/23 download Created with Sketch. 269.83KB
PAR Application for quotation of securities - PAR13/09/23 download Created with Sketch. 24.08KB
PAR Corporate Governance Statement01/09/23 download Created with Sketch. 217.79KB
PAR Appendix 4G01/09/23 download Created with Sketch. 261.77KB
PAR Notice of release of escrowed securities01/09/23 download Created with Sketch. 295.07KB
PAR Paradigm Accepted for Presentations at Major Conferences01/09/23 download Created with Sketch. 178.2KB
PAR 2023 Annual Report and Appendix 4EPRICE SENSITIVE25/08/23 download Created with Sketch. 3.3MB
PAR Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE31/07/23 download Created with Sketch. 373.8KB
PAR Study demonstrates Bene PPS is unique27/07/23 download Created with Sketch. 150.57KB
PAR Application for quotation of securities - PAR20/07/23 download Created with Sketch. 24.09KB
PAR Notice of release of escrowed securities10/07/23 download Created with Sketch. 295.36KB
PAR PAR Reports Phase 3 Clinical Trial UpdatePRICE SENSITIVE04/07/23 download Created with Sketch. 194.03KB
PAR Notification of cessation of securities - PAR29/06/23 download Created with Sketch. 23.45KB
PAR Primary and Secondary endpoints met in MPS I TrialPRICE SENSITIVE06/06/23 download Created with Sketch. 183.19KB
PAR iPPS shows 3-year equivalent durability in OA Canine StudyPRICE SENSITIVE01/06/23 download Created with Sketch. 423.9KB
PAR Change of Director's Interest Notice - Fisher22/05/23 download Created with Sketch. 174.52KB
PAR Change of Director's Interest Notice - Rennie17/05/23 download Created with Sketch. 178.57KB
PAR Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE28/04/23 download Created with Sketch. 327.15KB
PAR PAR Phase 2 MPS VI clinical trial completes enrolment28/04/23 download Created with Sketch. 253.64KB
PAR iPPS Demonstrates Multiple DMOAD Signals in Phase 2 StudyPRICE SENSITIVE04/04/23 download Created with Sketch. 5.73MB
PAR Trading HaltPRICE SENSITIVE31/03/23 download Created with Sketch. 624.8KB
PAR PAR Poster Presentation to OARSI World Congress 202328/03/23 download Created with Sketch. 514.15KB
PAR Notification of cessation of securities - PAR27/03/23 download Created with Sketch. 23.65KB
PAR NWR Virtual Healthcare Conference Presentation22/03/23 download Created with Sketch. 4.93MB
PAR Paradigm to present at the NWR Virtual Healthcare Conference21/03/23 download Created with Sketch. 121.14KB
PAR PAR Receives European Regulatory and Ethics Approval14/03/23 download Created with Sketch. 149.62KB
PAR Change of Chief Financial Officer03/03/23 download Created with Sketch. 135.11KB
PAR Notification of cessation of securities - PAR02/03/23 download Created with Sketch. 21.61KB
PAR Half Yearly Report and AccountsPRICE SENSITIVE27/02/23 download Created with Sketch. 2.25MB
PAR Paradigm Increases Presence at OARSI World Congress 202302/02/23 download Created with Sketch. 120.03KB
PAR Application for quotation of securities - PAR31/01/23 download Created with Sketch. 24.18KB
PAR Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE31/01/23 download Created with Sketch. 439.51KB
PAR Notice of release of escrowed securities19/01/23 download Created with Sketch. 254.64KB
PAR Paradigm Presentation to JP Morgan Healthcare Conference11/01/23 download Created with Sketch. 6.7MB
PAR Appendix 4G & 2022 Corporate Governance Statement10/01/23 download Created with Sketch. 454.66KB
PAR Notification of cessation of securities - PAR30/12/22 download Created with Sketch. 27.33KB
PAR Change in substantial holding
22/05/24 download Created with Sketch. 8.51MB
PAR Application for quotation of securities - PAR
20/05/24 download Created with Sketch. 15.51KB
PAR Quarterly Activities/Appendix 4C Cash Flow Report
30/04/24PRICE SENSITIVE download Created with Sketch. 325KB
PAR Notification of cessation of securities - PAR
26/04/24 download Created with Sketch. 13.22KB
PAR Type D Response Submitted and Received by the US FDA
19/04/24PRICE SENSITIVE download Created with Sketch. 157.42KB
PAR Notification of cessation of securities - PAR
05/04/24 download Created with Sketch. 13.23KB
PAR PAR to present at NWR Healthcare Conference
20/03/24 download Created with Sketch. 90.2KB
PAR Change of Director's Interest Notice
08/03/24 download Created with Sketch. 169.7KB
PAR Change of Director's Interest Notice
08/03/24 download Created with Sketch. 180.97KB
PAR Final Director's Interest Notice
06/03/24 download Created with Sketch. 150.9KB
PAR Initial Director's Interest Notice
04/03/24 download Created with Sketch. 157.18KB
PAR Paradigm Board Changes
04/03/24 download Created with Sketch. 135.46KB
PAR Notification regarding unquoted securities - PAR
29/02/24 download Created with Sketch. 16.25KB
PAR PAR Employee Performance Rights Plan Issue
29/02/24 download Created with Sketch. 112.65KB
PAR Half Yearly Report and Accounts
28/02/24PRICE SENSITIVE download Created with Sketch. 3.77MB
PAR Notification regarding unquoted securities - PAR
13/02/24 download Created with Sketch. 17.5KB
PAR Proposed issue of securities - PAR
12/02/24 download Created with Sketch. 23.96KB
PAR PAR Appoints Business Development Consultant
09/02/24 download Created with Sketch. 143.13KB
PAR Primary Endpoint Achieved in Phase 2 MPS VI Trial
09/02/24PRICE SENSITIVE download Created with Sketch. 387.82KB
PAR Paradigm Receives $7.36m R&D Tax Incentive Refund
07/02/24PRICE SENSITIVE download Created with Sketch. 61KB
PAR Quarterly Activities/Appendix 4C Cash Flow Report
31/01/24PRICE SENSITIVE download Created with Sketch. 350.17KB
PAR Notification of cessation of securities - PAR
30/01/24 download Created with Sketch. 21.97KB
PAR Application for quotation of securities - PAR
30/01/24 download Created with Sketch. 24.1KB
PAR PAR Selected for Major OA Conference Presentations
30/01/24 download Created with Sketch. 127.74KB
PAR Notice of release of escrowed securities
15/01/24 download Created with Sketch. 299.38KB
PAR Change in substantial holding
06/12/23 download Created with Sketch. 225.29KB
PAR Change of Director's Interest Notice - Fisher
01/12/23 download Created with Sketch. 175.33KB
PAR Change of Director's Interest Notice - Rennie
30/11/23 download Created with Sketch. 181.58KB
PAR Notification of cessation of securities - PAR
30/11/23 download Created with Sketch. 21.48KB
PAR Application for quotation of securities - PAR
30/11/23 download Created with Sketch. 24.73KB
PAR Results of Meeting
29/11/23 download Created with Sketch. 286.34KB
PAR 2023 AGM Company Update
29/11/23 download Created with Sketch. 5.6MB
PAR 2023 AGM Chairman Address
29/11/23 download Created with Sketch. 105.44KB
PAR Security Class Reinstatement to Quotation PARO
28/11/23PRICE SENSITIVE download Created with Sketch. 86.83KB
PAR Listing of Options - Top 20 Holders and Distribution Reports
27/11/23 download Created with Sketch. 77.91KB
PAR Application for quotation of securities - PAR
27/11/23 download Created with Sketch. 28.91KB
PAR Successful completion of Retail Entitlement Offer
23/11/23PRICE SENSITIVE download Created with Sketch. 138.29KB
PAR Security Class Suspension from Quotation PARO
21/11/23PRICE SENSITIVE download Created with Sketch. 89.1KB
PAR Application for quotation of securities - PAR
20/11/23 download Created with Sketch. 24.13KB
PAR PAR Pre-AGM Update
20/11/23 download Created with Sketch. 166.74KB
PAR Notice of release of escrowed securities
10/11/23 download Created with Sketch. 295.15KB
PAR Application for quotation of securities - PAR
08/11/23 download Created with Sketch. 26.91KB
PAR Retail Entitlement Offer Open
06/11/23 download Created with Sketch. 128.5KB
PAR Addendum to Notice of Meeting
03/11/23 download Created with Sketch. 693.49KB
PAR Paradigm to Recommence Trading
01/11/23PRICE SENSITIVE download Created with Sketch. 81.34KB
PAR Proposed issue of securities - PAR
31/10/23 download Created with Sketch. 30.43KB
PAR Update - Proposed issue of securities - PAR
31/10/23 download Created with Sketch. 48.67KB
PAR Replacement Entitlement Offer and Placement Prospectus
31/10/23PRICE SENSITIVE download Created with Sketch. 567.84KB
PAR PAR Successful Placement and Fully Underwritten ANREO
31/10/23PRICE SENSITIVE download Created with Sketch. 141.62KB
PAR Update - Proposed issue of securities - PAR
30/10/23 download Created with Sketch. 46.32KB
PAR Entitlement Offer and Placement Prospectus
30/10/23PRICE SENSITIVE download Created with Sketch. 525.55KB
PAR Proposed issue of securities - PAR
30/10/23 download Created with Sketch. 47.97KB
PAR Investor Presentation - $30m Capital Raise
30/10/23PRICE SENSITIVE download Created with Sketch. 10.88MB
PAR Paradigm Launches $30M Capital Raising
30/10/23PRICE SENSITIVE download Created with Sketch. 166.04KB
PAR Quarterly Activities/Appendix 4C Cash Flow Report
30/10/23PRICE SENSITIVE download Created with Sketch. 302.47KB
PAR Trading Halt
30/10/23PRICE SENSITIVE download Created with Sketch. 274.36KB
PAR Notice of Annual General Meeting/Proxy Form
25/10/23 download Created with Sketch. 467.1KB
PAR Final Director's Interest Notice
23/10/23 download Created with Sketch. 150.44KB
PAR Resignation of Non-executive Director
20/10/23 download Created with Sketch. 83.31KB
PAR iPPS Increases Cartilage Thickness in Phase 2 Trial
18/10/23PRICE SENSITIVE download Created with Sketch. 6.69MB
PAR Trading Halt
16/10/23PRICE SENSITIVE download Created with Sketch. 250.96KB
PAR iPPS SIGNIFICANT OA PAIN REDUCTION AT 12 MONTHS
10/10/23PRICE SENSITIVE download Created with Sketch. 7.37MB
PAR Trading Halt
06/10/23PRICE SENSITIVE download Created with Sketch. 259.19KB
PAR Date of AGM & Closing Date for Director Nominations
03/10/23 download Created with Sketch. 83.54KB
PAR Change of Share Registry Details
22/09/23 download Created with Sketch. 269.83KB
PAR Application for quotation of securities - PAR
13/09/23 download Created with Sketch. 24.08KB
PAR Corporate Governance Statement
01/09/23 download Created with Sketch. 217.79KB
PAR Appendix 4G
01/09/23 download Created with Sketch. 261.77KB
PAR Notice of release of escrowed securities
01/09/23 download Created with Sketch. 295.07KB
PAR Paradigm Accepted for Presentations at Major Conferences
01/09/23 download Created with Sketch. 178.2KB
PAR 2023 Annual Report and Appendix 4E
25/08/23PRICE SENSITIVE download Created with Sketch. 3.3MB
PAR Quarterly Activities/Appendix 4C Cash Flow Report
31/07/23PRICE SENSITIVE download Created with Sketch. 373.8KB
PAR Study demonstrates Bene PPS is unique
27/07/23 download Created with Sketch. 150.57KB
PAR Application for quotation of securities - PAR
20/07/23 download Created with Sketch. 24.09KB
PAR Notice of release of escrowed securities
10/07/23 download Created with Sketch. 295.36KB
PAR PAR Reports Phase 3 Clinical Trial Update
04/07/23PRICE SENSITIVE download Created with Sketch. 194.03KB
PAR Notification of cessation of securities - PAR
29/06/23 download Created with Sketch. 23.45KB
PAR Primary and Secondary endpoints met in MPS I Trial
06/06/23PRICE SENSITIVE download Created with Sketch. 183.19KB
PAR iPPS shows 3-year equivalent durability in OA Canine Study
01/06/23PRICE SENSITIVE download Created with Sketch. 423.9KB
PAR Change of Director's Interest Notice - Fisher
22/05/23 download Created with Sketch. 174.52KB
PAR Change of Director's Interest Notice - Rennie
17/05/23 download Created with Sketch. 178.57KB
PAR Quarterly Activities/Appendix 4C Cash Flow Report
28/04/23PRICE SENSITIVE download Created with Sketch. 327.15KB
PAR PAR Phase 2 MPS VI clinical trial completes enrolment
28/04/23 download Created with Sketch. 253.64KB
PAR iPPS Demonstrates Multiple DMOAD Signals in Phase 2 Study
04/04/23PRICE SENSITIVE download Created with Sketch. 5.73MB
PAR Trading Halt
31/03/23PRICE SENSITIVE download Created with Sketch. 624.8KB
PAR PAR Poster Presentation to OARSI World Congress 2023
28/03/23 download Created with Sketch. 514.15KB
PAR Notification of cessation of securities - PAR
27/03/23 download Created with Sketch. 23.65KB
PAR NWR Virtual Healthcare Conference Presentation
22/03/23 download Created with Sketch. 4.93MB
PAR Paradigm to present at the NWR Virtual Healthcare Conference
21/03/23 download Created with Sketch. 121.14KB
PAR PAR Receives European Regulatory and Ethics Approval
14/03/23 download Created with Sketch. 149.62KB
PAR Change of Chief Financial Officer
03/03/23 download Created with Sketch. 135.11KB
PAR Notification of cessation of securities - PAR
02/03/23 download Created with Sketch. 21.61KB
PAR Half Yearly Report and Accounts
27/02/23PRICE SENSITIVE download Created with Sketch. 2.25MB
PAR Paradigm Increases Presence at OARSI World Congress 2023
02/02/23 download Created with Sketch. 120.03KB
PAR Application for quotation of securities - PAR
31/01/23 download Created with Sketch. 24.18KB
PAR Quarterly Activities/Appendix 4C Cash Flow Report
31/01/23PRICE SENSITIVE download Created with Sketch. 439.51KB
PAR Notice of release of escrowed securities
19/01/23 download Created with Sketch. 254.64KB
PAR Paradigm Presentation to JP Morgan Healthcare Conference
11/01/23 download Created with Sketch. 6.7MB
PAR Appendix 4G & 2022 Corporate Governance Statement
10/01/23 download Created with Sketch. 454.66KB
PAR Notification of cessation of securities - PAR
30/12/22 download Created with Sketch. 27.33KB
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