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PARADIGM BIOPHARMACEUTICALS LIMITED.. - Announcements

Paradigm Biopharmaceuticals Limited is a late-stage drug development company. The Company... Paradigm Biopharmaceuticals Limited is a late-stage drug development company. The Company is engaged in discovering, developing, and delivering pharmaceutical therapies. It is focused on the development of injectable pentosan polysulfate sodium (iPPS/PPS) for the treatment of osteoarthritis (OA) and mucopolysaccharidosis (MPS). Pentosan polysulfate sodium is a semi-synthetic drug manufactured from the wood chips of European beech trees. Extracted glucurono-xylans are sulfated to produce a negatively charged product that mimics glycosaminoglycans (GAGs). It develops PPS under the brand name Zilosul. PPS also inhibits the synthesis of the metalloproteinase, MMP-3 (Troeberg) involved in degrading cartilage. PPS also include treatment of joint function, mobility, and pain in patients with MPS; treating alphavirus-induced arthralgia (such as Ross River virus and Chikungunya); chronic heart failure (HF) and acute respiratory distress syndrome (ARDS).More

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PAR Cleansing Notice and Appendix 2A16/04/20 download Created with Sketch. 451KB
PAR Reinstatement to Official QuotationPRICE SENSITIVE08/04/20 download Created with Sketch. 86.15KB
PAR Paradigm completes $35m raisingPRICE SENSITIVE08/04/20 download Created with Sketch. 160.78KB
PAR Proposed issue of Securities - PAR08/04/20 download Created with Sketch. 26.28KB
PAR PARADIGM TO HOST INVESTOR CALL07/04/20 download Created with Sketch. 186.82KB
PAR Paradigm Reports Very Encouraging Real World DataPRICE SENSITIVE06/04/20 download Created with Sketch. 334.99KB
PAR Paradigm receives clarity on US regulatory pathwayPRICE SENSITIVE06/04/20 download Created with Sketch. 212.2KB
PAR Paradigm Latest Corporate PresentationPRICE SENSITIVE06/04/20 download Created with Sketch. 4.61MB
PAR Voluntary SuspensionPRICE SENSITIVE06/04/20 download Created with Sketch. 224.5KB
PAR Trading HaltPRICE SENSITIVE02/04/20 download Created with Sketch. 559.31KB
PAR Appendix 3G24/03/20 download Created with Sketch. 371KB
PAR Paradigm to present at Virtual Conference, Friday 27th March24/03/20 download Created with Sketch. 143.86KB
PAR All 10 participants in US FDA EAP have commenced treatmentPRICE SENSITIVE24/03/20 download Created with Sketch. 280.06KB
PAR Change in substantial holding16/03/20 download Created with Sketch. 208.44KB
PAR Change of Director's Interest Notice16/03/20 download Created with Sketch. 161.2KB
PAR Appendix 3B and Appendix 3G28/02/20 download Created with Sketch. 672.18KB
PAR Paradigm reports Positive Pre-IND meeting with US FDAPRICE SENSITIVE21/02/20 download Created with Sketch. 104.33KB
PAR Paradigm - first patient dosed in USA under FDA approved EAPPRICE SENSITIVE18/02/20 download Created with Sketch. 463.42KB
PAR Half Yearly Report and AccountsPRICE SENSITIVE14/02/20 download Created with Sketch. 618.72KB
PAR Paradigm presents MPS VI poster at WORLD SymposiumPRICE SENSITIVE13/02/20 download Created with Sketch. 127.6KB
PAR Cleansing Notice and Appendix 2A10/02/20 download Created with Sketch. 377.6KB
PAR Cleansing Notice and Appendix 2A03/02/20 download Created with Sketch. 377.67KB
PAR Quarterly Update and Appendix 4C - quarterlyPRICE SENSITIVE31/01/20 download Created with Sketch. 231.02KB
PAR Updated Appendix 2A15/01/20 download Created with Sketch. 253.04KB
PAR Cleansing Notice14/01/20 download Created with Sketch. 148.97KB
PAR Appendix 2A14/01/20 download Created with Sketch. 252.93KB
PAR Cleansing Notice and Appendix 3BPRICE SENSITIVE18/12/19 download Created with Sketch. 690.74KB
PAR Cleansing Notice and Appendix 3B13/12/19 download Created with Sketch. 404.6KB
PAR Paradigm End of Calendar Year UpdatePRICE SENSITIVE12/12/19 download Created with Sketch. 109.38KB
PAR Cleansing Notice04/12/19 download Created with Sketch. 205.37KB
PAR Appendix 3B04/12/19 download Created with Sketch. 426.46KB
PAR Cleansing Notice and Appendix 3B25/11/19 download Created with Sketch. 397.52KB
PAR Change of Director's Interest Notice19/11/19 download Created with Sketch. 176.76KB
PAR Change in substantial holding14/11/19 download Created with Sketch. 193.39KB
PAR Change of Director's Interest Notice14/11/19 download Created with Sketch. 161.28KB
PAR Cleansing Notice and Appendix 3B11/11/19 download Created with Sketch. 396.78KB
PAR Results of Meeting07/11/19 download Created with Sketch. 201.62KB
PAR Paradigm AGM PresentationPRICE SENSITIVE07/11/19 download Created with Sketch. 1.05MB
PAR Quarterly Update and Appendix 4C - quarterlyPRICE SENSITIVE31/10/19 download Created with Sketch. 350.45KB
PAR PARADIGM PROVIDES REGULATORY FILING UPDATEPRICE SENSITIVE25/10/19 download Created with Sketch. 212.17KB
PAR Cleansing Notice and Appendix 3B22/10/19 download Created with Sketch. 1.01MB
PAR Notice of Annual General Meeting/Proxy Form04/10/19 download Created with Sketch. 376.19KB
PAR Cleansing Notice and Appendix 3B01/10/19 download Created with Sketch. 854.94KB
PAR Osteoarthritis pain reduced by Paradigms Zilosul (PPS)PRICE SENSITIVE30/09/19 download Created with Sketch. 371.09KB
PAR Cleansing Notice and Appendix 3B24/09/19 download Created with Sketch. 397.03KB
PAR Cleansing Notice and Appendix 3B17/09/19 download Created with Sketch. 1.01MB
PAR Cleansing Notice and Appendix 3B12/09/19 download Created with Sketch. 396.59KB
PAR PAR Expanded Access IND Cleared by US FDAPRICE SENSITIVE10/09/19 download Created with Sketch. 232.16KB
PAR Appendix 4G and 2019 Corporate Governance Statement30/08/19 download Created with Sketch. 403.85KB
PAR Appendix 4E and 2019 Annual ReportPRICE SENSITIVE30/08/19 download Created with Sketch. 1.12MB
PAR PARs drug reduces cartilage degradation in subjects with OAPRICE SENSITIVE29/08/19 download Created with Sketch. 1.19MB
PAR PARADIGM FILES FIRST IND WITH US FDAPRICE SENSITIVE07/08/19 download Created with Sketch. 146.39KB
PAR Appendix 4C - quarterlyPRICE SENSITIVE31/07/19 download Created with Sketch. 134.51KB
PAR Response to ASX Appendix 3Y Query05/07/19 download Created with Sketch. 522.29KB
PAR Change of Director's Interest Notice03/07/19 download Created with Sketch. 176.53KB
PAR Change in substantial holding02/07/19 download Created with Sketch. 382.01KB
PAR Change of Director's Interest Notice02/07/19 download Created with Sketch. 430.5KB
PAR Paradigm EOFY UpdatePRICE SENSITIVE28/06/19 download Created with Sketch. 326.67KB
PAR PAR REPORTS SUCCESSFUL ROSS RIVER PHASE 2 CLINICAL TRIALPRICE SENSITIVE04/06/19 download Created with Sketch. 408.29KB
PAR PAR reports consistent pain reduction in knee OA of patientsPRICE SENSITIVE28/05/19 download Created with Sketch. 352.81KB
PAR PAR CORRECTS AFR ARTICLEPRICE SENSITIVE21/05/19 download Created with Sketch. 83.76KB
PAR Updated Appendix 3B13/05/19 download Created with Sketch. 428.13KB
PAR Appendix 3B13/05/19 download Created with Sketch. 425.63KB
PAR Successful Completion of Retail Entitlement OfferPRICE SENSITIVE09/05/19 download Created with Sketch. 142.58KB
PAR Paradigm Corporate Update - May 2019PRICE SENSITIVE08/05/19 download Created with Sketch. 301.29KB
PAR Quarterly Report and Appendix 4C - quarterlyPRICE SENSITIVE30/04/19 download Created with Sketch. 1.22MB
PAR Appendix 3B26/04/19 download Created with Sketch. 279.04KB
PAR Cleansing Notice under section708A26/04/19 download Created with Sketch. 404.13KB
PAR Completion of Institutional Entitlement OfferPRICE SENSITIVE24/04/19 download Created with Sketch. 161.84KB
PAR Cleansing statement under Section 708AA24/04/19 download Created with Sketch. 156.1KB
PAR Change of Director's Interest Notice23/04/19 download Created with Sketch. 474.6KB
PAR PAR Accelerated Non-Renounceable Rights Issue Offer BookletPRICE SENSITIVE17/04/19 download Created with Sketch. 589.83KB
PAR Paradigm Confirms Capital Raise CommitmentsPRICE SENSITIVE17/04/19 download Created with Sketch. 104.96KB
PAR PARADIGM UPDATED CORPORATE PRESENTATIONPRICE SENSITIVE15/04/19 download Created with Sketch. 1.93MB
PAR Appendix 3B15/04/19 download Created with Sketch. 762.82KB
PAR PARADIGM LAUNCHES A$77.9M CAPITAL RAISEPRICE SENSITIVE15/04/19 download Created with Sketch. 100.11KB
PAR Cleansing statement under Section 708AA15/04/19 download Created with Sketch. 223.23KB
PAR Trading HaltPRICE SENSITIVE15/04/19 download Created with Sketch. 463.2KB
PAR PARADIGMS SECONDARY ENDPOINTS SUCCESSFULLY METPRICE SENSITIVE15/04/19 download Created with Sketch. 4.01MB
PAR Trading HaltPRICE SENSITIVE11/04/19 download Created with Sketch. 511.1KB
PAR Response to ASX Price QueryPRICE SENSITIVE28/03/19 download Created with Sketch. 675.46KB
PAR Paradigm (PAR) Updated Investor PresentationPRICE SENSITIVE13/03/19 download Created with Sketch. 19.1MB
PAR Change of Director's Interest Notice08/03/19 download Created with Sketch. 473.03KB
PAR S&P DJI Announces March 2019 Quarterly RebalancePRICE SENSITIVE08/03/19 download Created with Sketch. 175.31KB
PAR Half Yearly Report and AccountsPRICE SENSITIVE21/02/19 download Created with Sketch. 384.01KB
PAR Cleansing Notice and Appendix 3B14/02/19 download Created with Sketch. 953.72KB
PAR PARADIGMS ORPHAN PHASE 2/3 CLINICAL PROGRAM PROGRESSESPRICE SENSITIVE14/02/19 download Created with Sketch. 1.85MB
PAR Appendix 4C - quarterlyPRICE SENSITIVE31/01/19 download Created with Sketch. 423.18KB
PAR PARADIGMS SUPPLEMENTARY PHASE 2B DATAPRICE SENSITIVE20/12/18 download Created with Sketch. 812.37KB
PAR PRESENTATION OF PHASE 2 CLINICAL TRIAL RESULTSPRICE SENSITIVE18/12/18 download Created with Sketch. 3.09MB
PAR PAR REPORTS SUCCESSFUL PHASE 2 CLINICAL TRIALPRICE SENSITIVE18/12/18 download Created with Sketch. 576.83KB
PAR PAR - Conference Call Details - Phase 2b OA Results17/12/18 download Created with Sketch. 176.21KB
PAR Trading HaltPRICE SENSITIVE14/12/18 download Created with Sketch. 505.17KB
PAR Change in substantial holding13/12/18 download Created with Sketch. 154.21KB
PAR Change of Director's Interest Notice13/12/18 download Created with Sketch. 430.61KB
PAR Appendix 3B and Cleansing Notice13/12/18 download Created with Sketch. 952.71KB
PAR PARADIGM REPORTS CONSISTENT OA PAIN REDUCTIONPRICE SENSITIVE07/12/18 download Created with Sketch. 140.04KB
PAR Cleansing Notice and Appendix 3B30/11/18 download Created with Sketch. 953.33KB
PAR Cleansing Notice and Appendix 3B27/11/18 download Created with Sketch. 954.06KB
PAR Results of Meeting26/11/18 download Created with Sketch. 118.78KB
PAR Cleansing Notice and Appendix 2A
16/04/20 download Created with Sketch. 451KB
PAR Reinstatement to Official Quotation
08/04/20PRICE SENSITIVE download Created with Sketch. 86.15KB
PAR Paradigm completes $35m raising
08/04/20PRICE SENSITIVE download Created with Sketch. 160.78KB
PAR Proposed issue of Securities - PAR
08/04/20 download Created with Sketch. 26.28KB
PAR PARADIGM TO HOST INVESTOR CALL
07/04/20 download Created with Sketch. 186.82KB
PAR Paradigm Reports Very Encouraging Real World Data
06/04/20PRICE SENSITIVE download Created with Sketch. 334.99KB
PAR Paradigm receives clarity on US regulatory pathway
06/04/20PRICE SENSITIVE download Created with Sketch. 212.2KB
PAR Paradigm Latest Corporate Presentation
06/04/20PRICE SENSITIVE download Created with Sketch. 4.61MB
PAR Voluntary Suspension
06/04/20PRICE SENSITIVE download Created with Sketch. 224.5KB
PAR Trading Halt
02/04/20PRICE SENSITIVE download Created with Sketch. 559.31KB
PAR Appendix 3G
24/03/20 download Created with Sketch. 371KB
PAR Paradigm to present at Virtual Conference, Friday 27th March
24/03/20 download Created with Sketch. 143.86KB
PAR All 10 participants in US FDA EAP have commenced treatment
24/03/20PRICE SENSITIVE download Created with Sketch. 280.06KB
PAR Change in substantial holding
16/03/20 download Created with Sketch. 208.44KB
PAR Change of Director's Interest Notice
16/03/20 download Created with Sketch. 161.2KB
PAR Appendix 3B and Appendix 3G
28/02/20 download Created with Sketch. 672.18KB
PAR Paradigm reports Positive Pre-IND meeting with US FDA
21/02/20PRICE SENSITIVE download Created with Sketch. 104.33KB
PAR Paradigm - first patient dosed in USA under FDA approved EAP
18/02/20PRICE SENSITIVE download Created with Sketch. 463.42KB
PAR Half Yearly Report and Accounts
14/02/20PRICE SENSITIVE download Created with Sketch. 618.72KB
PAR Paradigm presents MPS VI poster at WORLD Symposium
13/02/20PRICE SENSITIVE download Created with Sketch. 127.6KB
PAR Cleansing Notice and Appendix 2A
10/02/20 download Created with Sketch. 377.6KB
PAR Cleansing Notice and Appendix 2A
03/02/20 download Created with Sketch. 377.67KB
PAR Quarterly Update and Appendix 4C - quarterly
31/01/20PRICE SENSITIVE download Created with Sketch. 231.02KB
PAR Updated Appendix 2A
15/01/20 download Created with Sketch. 253.04KB
PAR Cleansing Notice
14/01/20 download Created with Sketch. 148.97KB
PAR Appendix 2A
14/01/20 download Created with Sketch. 252.93KB
PAR Cleansing Notice and Appendix 3B
18/12/19PRICE SENSITIVE download Created with Sketch. 690.74KB
PAR Cleansing Notice and Appendix 3B
13/12/19 download Created with Sketch. 404.6KB
PAR Paradigm End of Calendar Year Update
12/12/19PRICE SENSITIVE download Created with Sketch. 109.38KB
PAR Cleansing Notice
04/12/19 download Created with Sketch. 205.37KB
PAR Appendix 3B
04/12/19 download Created with Sketch. 426.46KB
PAR Cleansing Notice and Appendix 3B
25/11/19 download Created with Sketch. 397.52KB
PAR Change of Director's Interest Notice
19/11/19 download Created with Sketch. 176.76KB
PAR Change in substantial holding
14/11/19 download Created with Sketch. 193.39KB
PAR Change of Director's Interest Notice
14/11/19 download Created with Sketch. 161.28KB
PAR Cleansing Notice and Appendix 3B
11/11/19 download Created with Sketch. 396.78KB
PAR Results of Meeting
07/11/19 download Created with Sketch. 201.62KB
PAR Paradigm AGM Presentation
07/11/19PRICE SENSITIVE download Created with Sketch. 1.05MB
PAR Quarterly Update and Appendix 4C - quarterly
31/10/19PRICE SENSITIVE download Created with Sketch. 350.45KB
PAR PARADIGM PROVIDES REGULATORY FILING UPDATE
25/10/19PRICE SENSITIVE download Created with Sketch. 212.17KB
PAR Cleansing Notice and Appendix 3B
22/10/19 download Created with Sketch. 1.01MB
PAR Notice of Annual General Meeting/Proxy Form
04/10/19 download Created with Sketch. 376.19KB
PAR Cleansing Notice and Appendix 3B
01/10/19 download Created with Sketch. 854.94KB
PAR Osteoarthritis pain reduced by Paradigms Zilosul (PPS)
30/09/19PRICE SENSITIVE download Created with Sketch. 371.09KB
PAR Cleansing Notice and Appendix 3B
24/09/19 download Created with Sketch. 397.03KB
PAR Cleansing Notice and Appendix 3B
17/09/19 download Created with Sketch. 1.01MB
PAR Cleansing Notice and Appendix 3B
12/09/19 download Created with Sketch. 396.59KB
PAR PAR Expanded Access IND Cleared by US FDA
10/09/19PRICE SENSITIVE download Created with Sketch. 232.16KB
PAR Appendix 4G and 2019 Corporate Governance Statement
30/08/19 download Created with Sketch. 403.85KB
PAR Appendix 4E and 2019 Annual Report
30/08/19PRICE SENSITIVE download Created with Sketch. 1.12MB
PAR PARs drug reduces cartilage degradation in subjects with OA
29/08/19PRICE SENSITIVE download Created with Sketch. 1.19MB
PAR PARADIGM FILES FIRST IND WITH US FDA
07/08/19PRICE SENSITIVE download Created with Sketch. 146.39KB
PAR Appendix 4C - quarterly
31/07/19PRICE SENSITIVE download Created with Sketch. 134.51KB
PAR Response to ASX Appendix 3Y Query
05/07/19 download Created with Sketch. 522.29KB
PAR Change of Director's Interest Notice
03/07/19 download Created with Sketch. 176.53KB
PAR Change in substantial holding
02/07/19 download Created with Sketch. 382.01KB
PAR Change of Director's Interest Notice
02/07/19 download Created with Sketch. 430.5KB
PAR Paradigm EOFY Update
28/06/19PRICE SENSITIVE download Created with Sketch. 326.67KB
PAR PAR REPORTS SUCCESSFUL ROSS RIVER PHASE 2 CLINICAL TRIAL
04/06/19PRICE SENSITIVE download Created with Sketch. 408.29KB
PAR PAR reports consistent pain reduction in knee OA of patients
28/05/19PRICE SENSITIVE download Created with Sketch. 352.81KB
PAR PAR CORRECTS AFR ARTICLE
21/05/19PRICE SENSITIVE download Created with Sketch. 83.76KB
PAR Updated Appendix 3B
13/05/19 download Created with Sketch. 428.13KB
PAR Appendix 3B
13/05/19 download Created with Sketch. 425.63KB
PAR Successful Completion of Retail Entitlement Offer
09/05/19PRICE SENSITIVE download Created with Sketch. 142.58KB
PAR Paradigm Corporate Update - May 2019
08/05/19PRICE SENSITIVE download Created with Sketch. 301.29KB
PAR Quarterly Report and Appendix 4C - quarterly
30/04/19PRICE SENSITIVE download Created with Sketch. 1.22MB
PAR Appendix 3B
26/04/19 download Created with Sketch. 279.04KB
PAR Cleansing Notice under section708A
26/04/19 download Created with Sketch. 404.13KB
PAR Completion of Institutional Entitlement Offer
24/04/19PRICE SENSITIVE download Created with Sketch. 161.84KB
PAR Cleansing statement under Section 708AA
24/04/19 download Created with Sketch. 156.1KB
PAR Change of Director's Interest Notice
23/04/19 download Created with Sketch. 474.6KB
PAR PAR Accelerated Non-Renounceable Rights Issue Offer Booklet
17/04/19PRICE SENSITIVE download Created with Sketch. 589.83KB
PAR Paradigm Confirms Capital Raise Commitments
17/04/19PRICE SENSITIVE download Created with Sketch. 104.96KB
PAR PARADIGM UPDATED CORPORATE PRESENTATION
15/04/19PRICE SENSITIVE download Created with Sketch. 1.93MB
PAR Appendix 3B
15/04/19 download Created with Sketch. 762.82KB
PAR PARADIGM LAUNCHES A$77.9M CAPITAL RAISE
15/04/19PRICE SENSITIVE download Created with Sketch. 100.11KB
PAR Cleansing statement under Section 708AA
15/04/19 download Created with Sketch. 223.23KB
PAR Trading Halt
15/04/19PRICE SENSITIVE download Created with Sketch. 463.2KB
PAR PARADIGMS SECONDARY ENDPOINTS SUCCESSFULLY MET
15/04/19PRICE SENSITIVE download Created with Sketch. 4.01MB
PAR Trading Halt
11/04/19PRICE SENSITIVE download Created with Sketch. 511.1KB
PAR Response to ASX Price Query
28/03/19PRICE SENSITIVE download Created with Sketch. 675.46KB
PAR Paradigm (PAR) Updated Investor Presentation
13/03/19PRICE SENSITIVE download Created with Sketch. 19.1MB
PAR Change of Director's Interest Notice
08/03/19 download Created with Sketch. 473.03KB
PAR S&P DJI Announces March 2019 Quarterly Rebalance
08/03/19PRICE SENSITIVE download Created with Sketch. 175.31KB
PAR Half Yearly Report and Accounts
21/02/19PRICE SENSITIVE download Created with Sketch. 384.01KB
PAR Cleansing Notice and Appendix 3B
14/02/19 download Created with Sketch. 953.72KB
PAR PARADIGMS ORPHAN PHASE 2/3 CLINICAL PROGRAM PROGRESSES
14/02/19PRICE SENSITIVE download Created with Sketch. 1.85MB
PAR Appendix 4C - quarterly
31/01/19PRICE SENSITIVE download Created with Sketch. 423.18KB
PAR PARADIGMS SUPPLEMENTARY PHASE 2B DATA
20/12/18PRICE SENSITIVE download Created with Sketch. 812.37KB
PAR PRESENTATION OF PHASE 2 CLINICAL TRIAL RESULTS
18/12/18PRICE SENSITIVE download Created with Sketch. 3.09MB
PAR PAR REPORTS SUCCESSFUL PHASE 2 CLINICAL TRIAL
18/12/18PRICE SENSITIVE download Created with Sketch. 576.83KB
PAR PAR - Conference Call Details - Phase 2b OA Results
17/12/18 download Created with Sketch. 176.21KB
PAR Trading Halt
14/12/18PRICE SENSITIVE download Created with Sketch. 505.17KB
PAR Change in substantial holding
13/12/18 download Created with Sketch. 154.21KB
PAR Change of Director's Interest Notice
13/12/18 download Created with Sketch. 430.61KB
PAR Appendix 3B and Cleansing Notice
13/12/18 download Created with Sketch. 952.71KB
PAR PARADIGM REPORTS CONSISTENT OA PAIN REDUCTION
07/12/18PRICE SENSITIVE download Created with Sketch. 140.04KB
PAR Cleansing Notice and Appendix 3B
30/11/18 download Created with Sketch. 953.33KB
PAR Cleansing Notice and Appendix 3B
27/11/18 download Created with Sketch. 954.06KB
PAR Results of Meeting
26/11/18 download Created with Sketch. 118.78KB
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