PAR 5.77% 24.5¢ paradigm biopharmaceuticals limited..

AGM 2024 - QUESTIONS, page-58

  1. 1,216 Posts.
    lightbulb Created with Sketch. 1375
    I think it's possible the DMC can simply recommend 2 x 2mg/kg and for the trial to move directly to stage 2. If this is the case then the stage 1 results will be used to establish 2 x 2mg/kg as the minimum effective dose, so won't be a complete waste. There will be a slight setback since the durability study will be delayed. The second option will be for PAR to go back to the FDA and get the IND amended to include 2 x 2mg/kg and possibly start from stage 1 again. It's obviously complicated since none of the P2 trials for iPPS have been conducted in the USA, but given the presumed lack of AE's in the stage 1 trial then the DMC should be confident enough to allow the 2 x 2mg/kg dose to be used.

    All IMO, dyor
 
watchlist Created with Sketch. Add PAR (ASX) to my watchlist
(20min delay)
Last
24.5¢
Change
-0.015(5.77%)
Mkt cap ! $85.70M
Open High Low Value Volume
26.0¢ 26.0¢ 24.5¢ $265.4K 1.050M

Buyers (Bids)

No. Vol. Price($)
8 130186 24.5¢
 

Sellers (Offers)

Price($) Vol. No.
25.0¢ 11571 1
View Market Depth
Last trade - 16.10pm 31/07/2024 (20 minute delay) ?
PAR (ASX) Chart
arrow-down-2 Created with Sketch. arrow-down-2 Created with Sketch.