Australia's largest stock trading and investment forum Australia's #1 stock forum

PAR

Click for more information

5.77%

24.5¢ paradigm biopharmaceuticals limited..

That could be problematic on several levels, not just the extra...

First 95 Last

Share
Profile

Follow
Zenox

1,216 Posts.

1375

20/09/22

12:28

Post #: 63791006
Share

Originally posted by Dungiven: ↑

I'm with you on this. Efficacy for pain and function is the main game. I think we have Safety well covered, so Efficacy on Pain and Function is what gets us a label, and makes PAR a market darling. That's a winning lottery ticket in itself.

The EAP results on WOMAC were great, but this 008 study of 60 people on WOMAC is all i'm thinking about. Biomarker activity is of course important, and might be extremely important going forward - but I want an encouraging lookthrough to 002 results from the Pain and Function data on WOMAC which will come from 008. If it's anything like the EAP results, it'll be extremely exciting. Like you, i'm worried that due to the nature of 008 (which included drawing synovium samples directly from the knee joint, a painful process) will impact the reporting of data for the secondary endpoints.

Expand

That could be problematic on several levels, not just the extra pain but the removal of synovial fluid that would contain factors that may heal or halt progression of OA, depending on how much synovial fluid is removed. I'm surprised PAR made pain and function a key secondary endpoint. While it's important to tie everything together, it might have been better to move it further down the order

PAR Price at posting: $1.18 Sentiment: Buy Disclosure: Held
1 Upvote

0 Great analysis

Reply

Top Stories

MGU

New results confirm Buena Vista's iron grades potential

MRC

Mineral Commodities to shut down Tormin mineral sands project as oil spill contaminates beach

KOB

Koba, formerly a cobalt player, gears up to become newest explorer in the uranium state: South Australia

1CG

One Click Group jumps 4% after ending quarter with $2.4M in cash; $1M in revenue and 150K+ users on board

Trimmed CPI figure provokes market jump of 1%, but inflation pressures remain a reality

There are more pages in this discussion • 15 more messages in this thread...

First 95 Last

Add PAR (ASX) to my watchlist

(20min delay)
Last 24.5¢		Change -0.015(5.77%)		Mkt cap ! $85.70M

Open	High	Low	Value	Volume
26.0¢	26.0¢	24.5¢	$265.4K	1.050M

Buyers (Bids)

No.	Vol.	Price($)
8	130186	24.5¢

Sellers (Offers)

Price($)	Vol.	No.
25.0¢	11571	1

View Market Depth

No.	Vol.	Price($)
8	130186	0.245
8	120363	0.240
5	126753	0.235
5	146782	0.230
2	53000	0.225

Price($)	Vol.	No.
0.250	11571	1
0.260	15236	1
0.265	59987	2
0.270	10000	1
0.275	16347	3

Last trade - 16.10pm 31/07/2024 (20 minute delay)

PAR (ASX) Chart