Ann: VIRALEZE Protects Against SARS-CoV-2 in Challenge Model, page-5

Well if the testing model was good enough for the vaccines and is endorsed by the World Health Organisation then it should surely further support TGA approval ?


The model used in this study of VIRALEZE™ is one of the few animal models endorsed by the World Health Organisation (WHO) to accelerate the testing of vaccines and therapeutic agents for COVID-19. 3 The transgenic mouse model expresses the human angiotensin converting enzyme (hACE2) receptor used by SARS-CoV-2 to infect cells in the human nasal cavity and respiratory tract.


I also liked this comment:

Collectively, these data illustrate, in this in vivo animal model, the ability of nasally administered VIRALEZE™ to inactivate virus and reduce viral load in the nose, trachea, lung and blood, and the resulting protective benefits of this action on the inflammatory cytokine response.

GLTAH