Hi GC,
Straight from the CEO ;-)
Hi Tony,
What we do with the high dose cohort will depend on what we see in the low dose cohort but, at this point, we're anticipating dosing for a longer period. As to the question about what we might be able to ascertain about an effect of NNZ-2566, if we didn't think there was a reasonable chance to detect a meaningful effect in 14 days, we wouldn't do it. Behavioral changes can occur quite quickly, particularly when they're so closely associated with an underlying physiological phenomenon. In the Fragile X model, for example, behavior was pretty much normalized within a week.
Larry
email reply from ceo, larry glass
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