following on from PJR82's link I went through and copied some of the studies that have been undertaken.
There are pages of it, so I just went through the first few pages.
Mind blowing stuff really, i hope it turns out.
Studies of Halloysite Clay Nanotubes.
Cytocompatibility and uptake of Nanotubes
Halloysite biocompatibility study is important for its potential applications in polymer composites, bone implants, controlled drug delivery, and for protective coating (e.g., anticorrosion or antimolding).
Halloysite Clay Nanotubes for Enzyme Immobilization
They are used for loading, storage, and controlled release of active chemical agents, including anticorrosions, biocides, and drugs.
Halloysite clay nanotubes for resveratrol delivery to cancer cells.
Halloysite is natural aluminosilicate clay with hollow tubular structure which allows loading with low soluble drugs using their saturated solutions in organic solvents.
Composite microparticles of halloysite clay nanotubes bound by calcium carbonate
Natural halloysite clay nanotubes with 15 nm inner and 75 nm outer diameters have been used as vehicles for sustained release of drugs in composite hollow microparticles.
Halloysite clay nanotubes for controlled delivery of chemically active agents
In this work we explored the capabilities of halloysite nanotubes as capsules for encapsulation and controlled delivery of the chemically and biologically active substances.
Application of halloysite clay nanotubes as a pharmaceutical excipient
Halloysite nanotubes, a biocompatible nanomaterial of 50-60nm diameter and ca. 15nm lumen, can be used for loading, storage and sustained release of drugs either in its pristine form or with additional polymer complexation for extended release time.
Release of surfactant cargo from interfacially-active halloysite clay nanotubes for oil spill remediation
Naturally occurring halloysite clay nanotubes are effective in stabilizing oil-in-water emulsions and can serve as interfacially-active vehicles for delivering oil spill treating agents.
Proteomic profiling of halloysite clay nanotube exposure in intestinal cell co-culture
Assessment of halloysite biocompatibility has gained importance in view of its potential application in oral drug delivery.
Halloysite Clay Nanotubes for Loading and Sustained Release of Functional Compounds
The inner lumen of halloysite may be adjusted by etching to 20-30% of the tube volume and loading with functional agents (antioxidants, anticorrosion agents, flame-retardant agents, drugs, or proteins) allowing for formulations with sustained release tuned by the tube end-stoppers for hours and days. Clogging the tube ends in polymeric composites allows further extension of the release time.
Hexagonal boron nitride nanoparticles decorated halloysite clay nanotubes as a potential hydrogen storage medium
The light weight and compact hydrogen storage materials is still prerequisite for the carbon free hydrogen fuel cell technology. In this work, the hydrogen storage performance of acid treated halloysite clay nanotubes
Paclitaxel Encapsulated in Halloysite Clay Nanotubes for Intestinal and Intracellular Delivery
Naturally formed halloysite tubules have a length of 1 μm and lumens with a diameter of 12-15 nm which can be loaded with drugs. Halloysite's biocompatibility allows for its safe delivering to cells at a concentration of up to 0.5 mg/mL. We encapsulated the anticancer drug paclitaxel in halloysite and evaluated the drug release kinetics in simulated gastric and intestinal conditions.
Halloysite nanotubule clay for efficient water purification
Halloysite exhibits higher adsorption capacity for both cationic and anionic dyes because it has negative SiO2 outermost and positive Al2O3 inner lumen surface; therefore, these clay nanotubes have efficient bivalent absorbency.
Halloysite Nanotubes for Cleaning, Consolidation and Protection
Herein, we report our recent research concerning the development of halloysite based protocols for cleaning, consolidation and protection purposes. Surface modification of halloysite cavity by anionic surfactants was explored to fabricate inorganic micelles able to solubilize hydrophobic contaminants
Self-healing coatings based on halloysite clay polymer composites for protection of copper alloys
Halloysite clay nanotubes loaded with corrosion inhibitors benzotriazole (BTA), 2-mercaptobenzimidazole (MBI), and 2-mercaptobenzothiazole (MBT) were used as additives in self-healing composite paint coating of copper.
Application of halloysite nanotubes for carbon dioxide capture
We investigated the potential applicability of HNTs for carbon dioxide (CO2) capture, These results show that inherent structural features of HNTs can be easily tailored for the development of operational condition-specific CO2 capture system.
Advances in rubber/halloysite nanotubes nanocomposites
The results showed that all the rubber/HNTs nanocomposites achieved strong interfacial interaction via interfacial covalent bonds, hydrogen bonds or multiple interactions, realized significantly improved dispersion of HNTs at nanoscale and exhibited excellent mechanical performances and other properties.
Highly aging-resistant elastomers doped with antioxidant-loaded clay nanotubes.
Loading the antioxidant inside of halloysite allows for its sustained release for nine months in the rubber matrix. By utilizing modified halloysite, the antioxidant concentration in this rubber Nano formulation is tripled without causing "blooming" defects.
Sustained Release of Antibacterial Agents from Doped Halloysite Nanotubes.
The use of nanomaterials for improving drug delivery methods has been shown to be advantageous technically and viable economically. This study employed the use of halloysite nanotubes (HNTs) as nanocontainers, as well as enhancers of structural integrity in electrospun poly-e-caprolactone (PCL) scaffolds.
Halloysite Nanotubes on Functional Pectin Bionanocomposites for Food Packaging Applications.
Pectin bionanocomposite films filled with various concentrations of two different types of halloysite nanotubes were prepared and characterized in this study as potential films for food packaging applications.
Electrospun microfiber membranes embedded with drug-loaded clay nanotubes for sustained antimicrobial protection.
Guided tissue regeneration/guided bone regeneration membranes with sustained drug delivery were developed by electrospinning drug-loaded halloysite clay nanotubes doped into poly(caprolactone)/gelatin microfibers.
Bacterial proliferation on clay nanotube Pickering emulsions for oil spill bioremediation.
Halloysites (tubular aluminosilicate) are introduced as inexpensive natural nanoparticles that form and stabilize oil-water emulsions. Pickering emulsification can proceed with energies low enough to be afforded by ocean turbulence and the stability of droplets extends over more than a week.
Thyme Oil Encapsulated in Halloysite Nanotubes for Antimicrobial Packaging System.
An antimicrobial capsule releasing thyme oil was developed using modified halloysite nanotubes (HNTs).
Polyethyleneimine grafted short halloysite nanotubes for gene delivery.
Inorganic nanoparticles have attracted much attentions in gene delivery because of their desirable characteristics including low toxicity, well-controlled characteristics, high gene delivery efficiency, and multi-functionalities. Here, natural occurred halloysite nanotubes (HNTs) were developed as a novel non-viral gene vector.
Competitive interactions and controlled release of a natural antioxidant from halloysite nanotubes.
Halloysite nanotubes used as potential carrier material for a controlled release stabilizer in polyethylene were thoroughly characterized with several techniques including the measurement of specific surface area, pore volume and surface energy. The high surface energy of the halloysite results in the strong bonding of the additive to the surface.
Halloysite nanotube-based electrospun ceramic nanofibre mat: a novel support for zeolite membranes
In this study, we fabricated millimetre-thick, self-standing electrospun ceramic nanofibre mats and employed them as a novel support for zeolite membranes.
Fabrication and evaluation of Bis-GMA/TEGDMA dental resins/composites containing halloysite nanotubes.
To investigate the reinforcement of Bis-GMA/TEGDMA dental resins (without conventional glass filler) and the corresponding composites (with conventional glass filler)containing vari ed mass fractions of halloysite nanotubes (HNTs).
Effect of barium-coated halloysite nanotube addition on the cytocompatibility, mechanical and contrast properties of poly(methyl methacrylate) cement.
Halloysite nanotubes (HNTs) were investigated as a platform for tunable nanoparticle composition and enhanced opacity in poly(methyl methacrylate) (PMMA) bone cement.
Polymerisation, antibacterial and bioactivity properties of experimental orthodontic adhesives containing triclosan-loaded halloysite nanotubes
To evaluate the immediate enamel bond strength, in situ degree of conversion and the polymerisation rate of three experimental orthodontic adhesives containing triclosan-loaded halloysite nanotubes. The antibacterial and bioactivity properties of such experimental materials were also assessed.
Doped Halloysite Nanotubes for Use in the 3D Printing of Medical Devices
This study explored the potential of 3D printing drug doped HNT constructs. We used a model drug, gentamicin (GS) and polylactic acid (PLA) to fabricate GS releasing disks, beads, and pellets.
Three-dimensionally interconnected Si frameworks derived from natural halloysite clay: a high-capacity anode material for lithium-ion batteries.
On account of its high theoretical capacity, silicon (Si) has been regarded as a promising anode material for Li-ion batteries. Extracting Si content from earth-abundant and low-cost aluminosilicate minerals, rather than from artificial silica (SiO2) precursors, is a more favorable and practical method for the large-scale application of Si anodes. In this work, three-dimensionally interconnected (3D-interconnected) Si frameworks with a branch diameter of ∼15 nm are prepared by the reduction of amorphous SiO2 nanotubes derived from natural halloysite clay.
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