Cosmetically focused research from Spain, noting its only theoretical and acknowledges further investigation is required. Its worth a mention that the lead author of the paper has several others relating to uses of natural clays/halloysite under various applications such as wound healing, drug delivery systems, skin care formulations etc.

Theoretical Study of Retinol, Niacinamide and Glycolic Acid with Halloysite Clay Mineral as Active Ingredients for Topical Skin Care Formulations (Molecules 2021, 26(15), 4392;) July 2021.

Extracted from conclusion:

Retinol, niacinamide and glycolic acid are molecules whose use is currently booming, due to the fact that they have a great variety of beneficial effects on the skin, like halloysite. The combined use of these aforementioned active ingredients with halloysite clay minerals may lead to formulations for skincare....

...Furthermore, retinol, niacinamide and glycolic acid were adsorbed inside the nanotube with an exothermic process, and the adsorption of these active ingredients on the confined halloysite surface was favourable. This indicates that retinol, niacinamide and glycolic acid could be experimentally adsorbed on the halloysite to obtain topical formulations for skincare.