Seems Pfizer has been working on how to avoid the disadvantages of HIV drug ritonavir in Paxlovid that doesn't treat SARS-CoV-2 but causes the severe adverse reactions to other medications that patients are taking and gives the drug the metallic taste that many hate.
So coming out of animal trials and into Phase 2 trials, they have a new drug which overcomes those issues.
https://pubs.acs.org/doi/epdf/10.1021/acs.jmedchem.3c02469
With the only alternative to Paxlovid, Merck's Lagevrio being less than 30% effective as a treatment and since 2023 not recommended by WHO, FDA and EMA, I guess Pfizer was aware regulators around the world were in a bind. As many people were now unable to have an effective treatment for coronavirus, antiviral nasal sprays like Viraleze might get approved as a Govt sponsored treatments ...
So just as TGA and the Health Minister might have needed Viraleze on the PBS - Pfizer is aiming for a new profitable covid treatment with escalated approval.
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Seems Pfizer has been working on how to avoid the disadvantages...
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