- Therapeutic dendrimer
Patent number: 12071517
Abstract: Provided herein are dendrimers comprising: a core unit, five generations of building units which are lysine residues or analogues thereof, first terminal groups comprising a cabazitazel residue covalently attached to a diglycolyl linker group, and second terminal groups comprising a PEG group. Also provided herein are pharmaceutical compositions comprising the dendrimers, and methods and uses of the dendrimers in therapy of disorders such as cancers. Processes for making the dendrimers and intermediates are also provided.
Type: Grant
Filed: August 30, 2021
Date of Patent: August 27, 2024
Assignee: Starpharma Pty Ltd.
Inventors: David James Owen, Brian Devlin Kelly, Jacinth Fairley, Jeremy Robert Arthur Paull, Stephanie Ruth Edmondson, Nicola Jane Main
Therapeutic dendrimer Patent number: 12071517 Abstract: Provided...
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