This link is to a Phelan McDermid Foundation podcast interviewing Dr Sue Fletcher and Dr Rebecca Simmons. It was back in March 2023 but seems to have only just surfaced. They give some good insight into the pre-clinical program. Scroll down the page to find the podcast.
https://podcasters.spotify.com/pod/show/phelan-mcdermid-syn/episodes/Dr--Sue-Fletcher-and-Dr--Rebecca-Simmons---Development-of-an-RNA-therapeutic-for-Phelan-McDermid-syndrome-e20sq8n
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