The paper demonstrates that no two manufacturing processes for PPS create a chemically similar product and that different preparations elicit different responses with respect to use of a PK activation assay and Factor XII activation assay, with the results showing bene's product being significantly less potent than the other PPS products tested. This may be ideal from a safety perspective since it appears these other products may pose a greater safety issue due to potential clotting risks.
The paper demonstrates that no two manufacturing processes for...
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