SPL starpharma holdings limited

SPL7013: A broad spectrum antiviral with massive future earning potential, page-2

  1. 62 Posts.
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    Thank you to all those who have responded to my post.

    I deleted the original post due to poor formatting and re-posted it on this newer thread, so please continue discussing on this newer thread, not the old one, so newcomers can follow the discussion from the start.

    I disagree with those who propose the nasal spray (assuming it is proven to be effective clinically) is likely to be just a flash in the pan or to be rendered useless once COVID vaccines are developed.

    Also, I believe that SPL7013 is a remarkable molecule having such a BROAD SPECTRUM antiviral activity and that there is massive future potential for a whole range of viruses via various modes of delivery: nasal (respiratory viruses); ocular (viral conjunctivitis and respiratory viruses); injected (severe illness from respiratory viruses such as COVID, Influenza and other non-respiratory viruses).

    Available effective antivirals are limited in number and generally fairly narrow spectrum. This is why I find SPL7013 such an exciting molecule!

    I would like to make a few further points regarding just the nasal spray application:

    NASAL SPRAY COVID MARKET:

    In the short to medium term, I think it is very likely to be used during the pandemic and beyond, even when vaccines are available. Vaccines are likely to be only partly protective and will take a very long time to roll out on a global scale. Even if vaccinated, high risk people (health workers, immunosuppressed, chronic airways disease, etc) would value the additional protection of the SPL7013 spray (and possibly drops when available) against COVID. Family members of high risk people may also wish to avail themselves of the added protection from (and potentially reduced transmission of) respiratory viruses such a product could provide, to protect their loved ones.

    In the long term, as per my detailed post above, COVID will almost certainly persist well beyond the pandemic and the spray may be needed to provide added protection, as an adjunct to vaccines for those groups listed above, where there are future outbreaks.

    Many people may choose not to vaccinate against COVID but may then prefer to use the nasal spray instead.

    OTHER RESPIRATORY VIRUSES:

    I believe there is potentially a very, very large long-term market for the nasal spray because it is BROAD SPECTRUM. Look at the list of viruses it has been found to be active against, so far.

    BROAD SPECTRUM effectiveness makes it the perfect agent to stockpile for future pandemic preparedness.

    Influenza is a serious seasonal illness, causing many thousands of people in Australia (and millions around the world) to become ill, or die, every year, despite widely available vaccines. Future influenza epidemics and pandemics are inevitable, despite vaccines.

    Currently there is no vaccine against the common cold (caused mostly by coronaviruses and rhinoviruses). As far as I know, SPL7013 has not yet been tested against rhinoviruses, but that will no doubt be done at some stage. One would expect the nasal spray to be active against the common-cold causing coronaviruses.

    For all the reasons above, I believe that pre-exposure prophylaxis (PREP) is likely to become a standard use of the nasal spray for high risk groups against a whole range of respiratory viruses long into the future, well beyond the covid pandemic. For example, taking a couple of sprays before flying on a plane, or even going to the supermarket.

    I also believe that nasal spray post-exposure prophylaxis (PEP) against any respiratory virus is quite likely to become very popular among the general population, judging by the huge sales of OTC cough/cold medications. As per my previous post, most of these products either have no evidence of effectiveness or only provide partial symptomatic relief. If one family member develops a cold, other family members could use the nasal spray to reduce the risk of them also contracting the same illness.

    ? Treatment for the common cold: It will be really interesting to find out, in the future, if such a nasal spray could shorten a respiratory illness, or make it less severe, if started after the onset of symptoms. A treatment for the common cold is one of the holy grails of medicine!
 
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