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PYC

PYC THERAPEUTICS LIMITED - Announcements

0.42% ! $1.19
Market Cap $691.1M  !

PYC Therapeutics Limited is an Australia-based clinical-stage biotechnology company... PYC Therapeutics Limited is an Australia-based clinical-stage biotechnology company creating a new generation of ribonucleic acid (RNA) therapies to change the lives of patients with genetic diseases. The Company utilizes its proprietary drug delivery platform to enhance the potency of precision medicines within the rapidly growing and commercially proven RNA therapeutic class. Its drug development programs target monogenic diseases - the indications with the highest likelihood of success in clinical development. Its first-in-class drug programs include Retinitis Pigmentosa type 11, (VP-001), Polycystic Kidney Disease, (PYC-003), Autosomal Dominant Optic Atrophy (ADOA) (PYC-001) and Phelan-McDermid Syndrome (PMS) (PYC-002). The Company's VP-001 program is a lead asset for a blinding eye disease of childhood progressed through multiple patient cohorts in the ongoing single ascending dose clinical trial. ADOA is a progressive and blinding eye disease.More

Announcements



PYC SRC Approves Dose Escalation in ADOA Clinical TrialPRICE SENSITIVE11/06/25 download Created with Sketch. 377.2KB
PYC Investor Webinar Presentation30/05/25 download Created with Sketch. 726.61KB
PYC Approval to Escalate Dosing in Kidney Disease TrialPRICE SENSITIVE26/05/25 download Created with Sketch. 507.43KB
PYC Notification of cessation of securities - PYC23/05/25 download Created with Sketch. 14.87KB
PYC Q2 Investor Webinar 30 May 202513/05/25 download Created with Sketch. 236.08KB
PYC Foundation Fighting Blindness Presentation Materials02/05/25 download Created with Sketch. 2.02MB
PYC Change in substantial holding28/04/25 download Created with Sketch. 194.96KB
PYC Presentation of Clinical Proof of Concept in Lead ProgramPRICE SENSITIVE28/04/25 download Created with Sketch. 854.95KB
PYC Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE24/04/25 download Created with Sketch. 465.75KB
PYC Application for quotation of securities - PYC23/04/25 download Created with Sketch. 14.2KB
PYC Completion of Entitlement OfferPRICE SENSITIVE17/04/25 download Created with Sketch. 219.2KB
PYC First Subject Dosed in PKD Clinical TrialPRICE SENSITIVE10/04/25 download Created with Sketch. 441.03KB
PYC Placement of ShortfallPRICE SENSITIVE09/04/25 download Created with Sketch. 216.79KB
PYC Investor Webinar Presentation28/03/25 download Created with Sketch. 729.09KB
PYC Application for quotation of securities - PYC21/03/25 download Created with Sketch. 15.7KB
PYC Q1 Investor Webinar 28 March 202521/03/25 download Created with Sketch. 257.31KB
PYC Completion of Retail Entitlement OfferPRICE SENSITIVE18/03/25 download Created with Sketch. 236.19KB
PYC Change of Director's Interest Notice27/02/25 download Created with Sketch. 250.11KB
PYC Ceasing to be a substantial holder27/02/25 download Created with Sketch. 178.13KB
PYC Half Yearly Report and AccountsPRICE SENSITIVE27/02/25 download Created with Sketch. 819.41KB
PYC Application for quotation of securities - PYC26/02/25 download Created with Sketch. 14.36KB
PYC Despatch of Notice to Ineligible Retail Shareholders24/02/25 download Created with Sketch. 445.37KB
PYC Despatch of Retail Offer Document24/02/25 download Created with Sketch. 198.84KB
PYC Retail Entitlement Offer BookletPRICE SENSITIVE24/02/25 download Created with Sketch. 1.78MB
PYC Completion of Institutional Entitlement OfferPRICE SENSITIVE19/02/25 download Created with Sketch. 253.16KB
PYC Cleansing Notice Under Section 708AA17/02/25 download Created with Sketch. 225.4KB
PYC Proposed issue of securities - PYC17/02/25 download Created with Sketch. 22.11KB
PYC PYC Equity Raising PresentationPRICE SENSITIVE17/02/25 download Created with Sketch. 874.52KB
PYC PYC Equity Raising to Raise up to $146 MillionPRICE SENSITIVE17/02/25 download Created with Sketch. 278.79KB
PYC Trading HaltPRICE SENSITIVE17/02/25 download Created with Sketch. 257.19KB
PYC Approval to Commence Human Trials in Kidney ProgramPRICE SENSITIVE10/02/25 download Created with Sketch. 324.62KB
PYC Notification of cessation of securities - PYC03/02/25 download Created with Sketch. 13.41KB
PYC ADOA Safety Review Committee Approves Dose EscalationPRICE SENSITIVE31/01/25 download Created with Sketch. 257.38KB
PYC Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE29/01/25 download Created with Sketch. 580.07KB
PYC US FDA Grants Rare Pediatric Disease Designation to VP-001PRICE SENSITIVE20/01/25 download Created with Sketch. 224.02KB
PYC PYC Nominates Fourth Clinical Drug Candidate in PMS ProgramPRICE SENSITIVE16/12/24 download Created with Sketch. 339.93KB
PYC Polycystic Kidney Disease Program Investor Presentation28/11/24 download Created with Sketch. 1.06MB
PYC Notification of cessation of securities - PYC27/11/24 download Created with Sketch. 12.87KB
PYC Notification regarding unquoted securities - PYC27/11/24 download Created with Sketch. 17.82KB
PYC Change of Director's Interest Notice27/11/24 download Created with Sketch. 223.88KB
PYC PYC to Progress Kidney Drug Candidate Into Human TrialsPRICE SENSITIVE27/11/24 download Created with Sketch. 2.52MB
PYC Presentation of RP11 Clinical Trial Data at APVRS 2024PRICE SENSITIVE22/11/24 download Created with Sketch. 1.31MB
PYC Completion of Share Consolidation21/11/24 download Created with Sketch. 176.7KB
PYC Share Consolidation and ASX Code14/11/24 download Created with Sketch. 163.11KB
PYC Update - Consolidation/Split - PYC13/11/24 download Created with Sketch. 22.48KB
PYC Results of Annual General Meeting13/11/24 download Created with Sketch. 209.81KB
PYC 2024 AGM Chairman's Address and CEO Presentation13/11/24 download Created with Sketch. 768.98KB
PYC Consolidation/Split - PYCPRICE SENSITIVE11/11/24 download Created with Sketch. 23.15KB
PYC Annual General Meeting - Conference Call Details06/11/24 download Created with Sketch. 183.91KB
PYC RP11 SRC Approves Dose Escalation to Final Patient CohortPRICE SENSITIVE05/11/24 download Created with Sketch. 259.08KB
PYC First ADOA Patient Dosed in Clinical TrialPRICE SENSITIVE01/11/24 download Created with Sketch. 279.88KB
PYC Presentation of RP11 Single Dose Data at RANZCO31/10/24 download Created with Sketch. 228.31KB
PYC Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE25/10/24 download Created with Sketch. 580.87KB
PYC Interim Update on Progress in RP11 Repeat Dose TrialsPRICE SENSITIVE22/10/24 download Created with Sketch. 272.88KB
PYC Trading HaltPRICE SENSITIVE21/10/24 download Created with Sketch. 561.45KB
PYC US FDA Grants Orphan Drug Designation to PYC Drug CandidatePRICE SENSITIVE21/10/24 download Created with Sketch. 232.46KB
PYC Notice of Annual General Meeting/Proxy FormPRICE SENSITIVE14/10/24 download Created with Sketch. 677.61KB
PYC 2024 Corporate Governance Statement & Appendix 4G09/10/24 download Created with Sketch. 904.29KB
PYC Annual Report to shareholders09/10/24 download Created with Sketch. 2.52MB
PYC E&P Healthcare Conference Presentation26/09/24 download Created with Sketch. 885.93KB
PYC FDA Grants Rare Pediatric Disease Designation to PYC-001PRICE SENSITIVE30/08/24 download Created with Sketch. 247.98KB
PYC Q3 2024 Investor Webinar Presentation30/08/24 download Created with Sketch. 990.99KB
PYC Appendix 4E and Audited Financial StatementsPRICE SENSITIVE29/08/24 download Created with Sketch. 1.09MB
PYC Q3 Investor Webinar 30 August 202422/08/24 download Created with Sketch. 220.73KB
PYC PYC to Start Human Trials in Second Blinding Eye DiseasePRICE SENSITIVE15/08/24 download Created with Sketch. 273.11KB
PYC Canaccord Genuity Growth Conference Presentation13/08/24 download Created with Sketch. 1.4MB
PYC Visual Improvement in Multiple RP11 PatientsPRICE SENSITIVE12/08/24 download Created with Sketch. 377.55KB
PYC RP11 Clinical Trial Update - AmendedPRICE SENSITIVE05/08/24 download Created with Sketch. 863.26KB
PYC RP11 Clinical Trial UpdatePRICE SENSITIVE05/08/24 download Created with Sketch. 666KB
PYC Completion of Small Shareholding Sale Facility02/08/24 download Created with Sketch. 196.97KB
PYC Extension of RP11 Single Dose Study Into Multiple Dose StudyPRICE SENSITIVE23/07/24 download Created with Sketch. 336.36KB
PYC Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE22/07/24 download Created with Sketch. 534.97KB
PYC Initial Dosing Completed in Cohort 1 of RP11 MAD StudyPRICE SENSITIVE17/07/24 download Created with Sketch. 382.77KB
PYC Bioshares Biotech Summit Presentation12/07/24 download Created with Sketch. 1.16MB
PYC Commencement of RP11 Multiple Dose TrialPRICE SENSITIVE10/07/24 download Created with Sketch. 397.55KB
PYC Notification regarding unquoted securities - PYC02/07/24 download Created with Sketch. 17.61KB
PYC RP11 Drug Candidate Safe and Well ToleratedPRICE SENSITIVE01/07/24 download Created with Sketch. 240.23KB
PYC PMS Drug Candidate Effective In Human Brain CellsPRICE SENSITIVE07/06/24 download Created with Sketch. 297.34KB
PYC US FDA Grants Orphan Drug Designation to PYC Drug CandidatePRICE SENSITIVE24/05/24 download Created with Sketch. 221.82KB
PYC Small Shareholdings Sale Facility24/05/24 download Created with Sketch. 607.56KB
PYC Issue of Options23/05/24 download Created with Sketch. 260.26KB
PYC Notification regarding unquoted securities - PYC23/05/24 download Created with Sketch. 16.88KB
PYC Change in substantial holding17/05/24 download Created with Sketch. 191.02KB
PYC Change of Director's Interest Notice17/05/24 download Created with Sketch. 250.05KB
PYC RP11 Clinical Trial Dosing Completed in Cohort 4PRICE SENSITIVE16/05/24 download Created with Sketch. 480.02KB
PYC Successful GLP Tox Studies in Second Blinding Eye DiseasePRICE SENSITIVE14/05/24 download Created with Sketch. 378.74KB
PYC Q2 2024 Investor Webinar Presentation09/05/24 download Created with Sketch. 726.44KB
PYC Presentation of RP11 Clinical Trial Data at ARVO ConferencePRICE SENSITIVE06/05/24 download Created with Sketch. 1.4MB
PYC Ceasing to be a substantial holder01/05/24 download Created with Sketch. 89.23KB
PYC Q2 Investor Webinar 9 May 202401/05/24 download Created with Sketch. 220.33KB
PYC Application for quotation of securities - PYC30/04/24 download Created with Sketch. 15.49KB
PYC RP11 Drug Candidate Progressing to Mid-Stage Human TrialsPRICE SENSITIVE29/04/24 download Created with Sketch. 281.37KB
PYC Quarterly Activities/Appendix 4C Cash Flow ReportPRICE SENSITIVE26/04/24 download Created with Sketch. 375.34KB
PYC Kidney Disease Drug Candidate Progressing to Human TrialsPRICE SENSITIVE22/04/24 download Created with Sketch. 280.51KB
PYC Change in substantial holding17/04/24 download Created with Sketch. 193.75KB
PYC Update - Application for quotation of securities - PYC15/04/24 download Created with Sketch. 15.66KB
PYC Application for quotation of securities - PYC12/04/24 download Created with Sketch. 14.27KB
PYC Change in substantial holding11/04/24 download Created with Sketch. 101.29KB
PYC $74.6 Million Extension of Cash RunwayPRICE SENSITIVE10/04/24 download Created with Sketch. 248.55KB
PYC Notification of cessation of securities - PYC03/04/24 download Created with Sketch. 12.93KB
PYC SRC Approves Dose Escalation in ADOA Clinical Trial
11/06/25PRICE SENSITIVE download Created with Sketch. 377.2KB
PYC Investor Webinar Presentation
30/05/25 download Created with Sketch. 726.61KB
PYC Approval to Escalate Dosing in Kidney Disease Trial
26/05/25PRICE SENSITIVE download Created with Sketch. 507.43KB
PYC Notification of cessation of securities - PYC
23/05/25 download Created with Sketch. 14.87KB
PYC Q2 Investor Webinar 30 May 2025
13/05/25 download Created with Sketch. 236.08KB
PYC Foundation Fighting Blindness Presentation Materials
02/05/25 download Created with Sketch. 2.02MB
PYC Change in substantial holding
28/04/25 download Created with Sketch. 194.96KB
PYC Presentation of Clinical Proof of Concept in Lead Program
28/04/25PRICE SENSITIVE download Created with Sketch. 854.95KB
PYC Quarterly Activities/Appendix 4C Cash Flow Report
24/04/25PRICE SENSITIVE download Created with Sketch. 465.75KB
PYC Application for quotation of securities - PYC
23/04/25 download Created with Sketch. 14.2KB
PYC Completion of Entitlement Offer
17/04/25PRICE SENSITIVE download Created with Sketch. 219.2KB
PYC First Subject Dosed in PKD Clinical Trial
10/04/25PRICE SENSITIVE download Created with Sketch. 441.03KB
PYC Placement of Shortfall
09/04/25PRICE SENSITIVE download Created with Sketch. 216.79KB
PYC Investor Webinar Presentation
28/03/25 download Created with Sketch. 729.09KB
PYC Application for quotation of securities - PYC
21/03/25 download Created with Sketch. 15.7KB
PYC Q1 Investor Webinar 28 March 2025
21/03/25 download Created with Sketch. 257.31KB
PYC Completion of Retail Entitlement Offer
18/03/25PRICE SENSITIVE download Created with Sketch. 236.19KB
PYC Change of Director's Interest Notice
27/02/25 download Created with Sketch. 250.11KB
PYC Ceasing to be a substantial holder
27/02/25 download Created with Sketch. 178.13KB
PYC Half Yearly Report and Accounts
27/02/25PRICE SENSITIVE download Created with Sketch. 819.41KB
PYC Application for quotation of securities - PYC
26/02/25 download Created with Sketch. 14.36KB
PYC Despatch of Notice to Ineligible Retail Shareholders
24/02/25 download Created with Sketch. 445.37KB
PYC Despatch of Retail Offer Document
24/02/25 download Created with Sketch. 198.84KB
PYC Retail Entitlement Offer Booklet
24/02/25PRICE SENSITIVE download Created with Sketch. 1.78MB
PYC Completion of Institutional Entitlement Offer
19/02/25PRICE SENSITIVE download Created with Sketch. 253.16KB
PYC Cleansing Notice Under Section 708AA
17/02/25 download Created with Sketch. 225.4KB
PYC Proposed issue of securities - PYC
17/02/25 download Created with Sketch. 22.11KB
PYC PYC Equity Raising Presentation
17/02/25PRICE SENSITIVE download Created with Sketch. 874.52KB
PYC PYC Equity Raising to Raise up to $146 Million
17/02/25PRICE SENSITIVE download Created with Sketch. 278.79KB
PYC Trading Halt
17/02/25PRICE SENSITIVE download Created with Sketch. 257.19KB
PYC Approval to Commence Human Trials in Kidney Program
10/02/25PRICE SENSITIVE download Created with Sketch. 324.62KB
PYC Notification of cessation of securities - PYC
03/02/25 download Created with Sketch. 13.41KB
PYC ADOA Safety Review Committee Approves Dose Escalation
31/01/25PRICE SENSITIVE download Created with Sketch. 257.38KB
PYC Quarterly Activities/Appendix 4C Cash Flow Report
29/01/25PRICE SENSITIVE download Created with Sketch. 580.07KB
PYC US FDA Grants Rare Pediatric Disease Designation to VP-001
20/01/25PRICE SENSITIVE download Created with Sketch. 224.02KB
PYC PYC Nominates Fourth Clinical Drug Candidate in PMS Program
16/12/24PRICE SENSITIVE download Created with Sketch. 339.93KB
PYC Polycystic Kidney Disease Program Investor Presentation
28/11/24 download Created with Sketch. 1.06MB
PYC Notification of cessation of securities - PYC
27/11/24 download Created with Sketch. 12.87KB
PYC Notification regarding unquoted securities - PYC
27/11/24 download Created with Sketch. 17.82KB
PYC Change of Director's Interest Notice
27/11/24 download Created with Sketch. 223.88KB
PYC PYC to Progress Kidney Drug Candidate Into Human Trials
27/11/24PRICE SENSITIVE download Created with Sketch. 2.52MB
PYC Presentation of RP11 Clinical Trial Data at APVRS 2024
22/11/24PRICE SENSITIVE download Created with Sketch. 1.31MB
PYC Completion of Share Consolidation
21/11/24 download Created with Sketch. 176.7KB
PYC Share Consolidation and ASX Code
14/11/24 download Created with Sketch. 163.11KB
PYC Update - Consolidation/Split - PYC
13/11/24 download Created with Sketch. 22.48KB
PYC Results of Annual General Meeting
13/11/24 download Created with Sketch. 209.81KB
PYC 2024 AGM Chairman's Address and CEO Presentation
13/11/24 download Created with Sketch. 768.98KB
PYC Consolidation/Split - PYC
11/11/24PRICE SENSITIVE download Created with Sketch. 23.15KB
PYC Annual General Meeting - Conference Call Details
06/11/24 download Created with Sketch. 183.91KB
PYC RP11 SRC Approves Dose Escalation to Final Patient Cohort
05/11/24PRICE SENSITIVE download Created with Sketch. 259.08KB
PYC First ADOA Patient Dosed in Clinical Trial
01/11/24PRICE SENSITIVE download Created with Sketch. 279.88KB
PYC Presentation of RP11 Single Dose Data at RANZCO
31/10/24 download Created with Sketch. 228.31KB
PYC Quarterly Activities/Appendix 4C Cash Flow Report
25/10/24PRICE SENSITIVE download Created with Sketch. 580.87KB
PYC Interim Update on Progress in RP11 Repeat Dose Trials
22/10/24PRICE SENSITIVE download Created with Sketch. 272.88KB
PYC Trading Halt
21/10/24PRICE SENSITIVE download Created with Sketch. 561.45KB
PYC US FDA Grants Orphan Drug Designation to PYC Drug Candidate
21/10/24PRICE SENSITIVE download Created with Sketch. 232.46KB
PYC Notice of Annual General Meeting/Proxy Form
14/10/24PRICE SENSITIVE download Created with Sketch. 677.61KB
PYC 2024 Corporate Governance Statement & Appendix 4G
09/10/24 download Created with Sketch. 904.29KB
PYC Annual Report to shareholders
09/10/24 download Created with Sketch. 2.52MB
PYC E&P Healthcare Conference Presentation
26/09/24 download Created with Sketch. 885.93KB
PYC FDA Grants Rare Pediatric Disease Designation to PYC-001
30/08/24PRICE SENSITIVE download Created with Sketch. 247.98KB
PYC Q3 2024 Investor Webinar Presentation
30/08/24 download Created with Sketch. 990.99KB
PYC Appendix 4E and Audited Financial Statements
29/08/24PRICE SENSITIVE download Created with Sketch. 1.09MB
PYC Q3 Investor Webinar 30 August 2024
22/08/24 download Created with Sketch. 220.73KB
PYC PYC to Start Human Trials in Second Blinding Eye Disease
15/08/24PRICE SENSITIVE download Created with Sketch. 273.11KB
PYC Canaccord Genuity Growth Conference Presentation
13/08/24 download Created with Sketch. 1.4MB
PYC Visual Improvement in Multiple RP11 Patients
12/08/24PRICE SENSITIVE download Created with Sketch. 377.55KB
PYC RP11 Clinical Trial Update - Amended
05/08/24PRICE SENSITIVE download Created with Sketch. 863.26KB
PYC RP11 Clinical Trial Update
05/08/24PRICE SENSITIVE download Created with Sketch. 666KB
PYC Completion of Small Shareholding Sale Facility
02/08/24 download Created with Sketch. 196.97KB
PYC Extension of RP11 Single Dose Study Into Multiple Dose Study
23/07/24PRICE SENSITIVE download Created with Sketch. 336.36KB
PYC Quarterly Activities/Appendix 4C Cash Flow Report
22/07/24PRICE SENSITIVE download Created with Sketch. 534.97KB
PYC Initial Dosing Completed in Cohort 1 of RP11 MAD Study
17/07/24PRICE SENSITIVE download Created with Sketch. 382.77KB
PYC Bioshares Biotech Summit Presentation
12/07/24 download Created with Sketch. 1.16MB
PYC Commencement of RP11 Multiple Dose Trial
10/07/24PRICE SENSITIVE download Created with Sketch. 397.55KB
PYC Notification regarding unquoted securities - PYC
02/07/24 download Created with Sketch. 17.61KB
PYC RP11 Drug Candidate Safe and Well Tolerated
01/07/24PRICE SENSITIVE download Created with Sketch. 240.23KB
PYC PMS Drug Candidate Effective In Human Brain Cells
07/06/24PRICE SENSITIVE download Created with Sketch. 297.34KB
PYC US FDA Grants Orphan Drug Designation to PYC Drug Candidate
24/05/24PRICE SENSITIVE download Created with Sketch. 221.82KB
PYC Small Shareholdings Sale Facility
24/05/24 download Created with Sketch. 607.56KB
PYC Issue of Options
23/05/24 download Created with Sketch. 260.26KB
PYC Notification regarding unquoted securities - PYC
23/05/24 download Created with Sketch. 16.88KB
PYC Change in substantial holding
17/05/24 download Created with Sketch. 191.02KB
PYC Change of Director's Interest Notice
17/05/24 download Created with Sketch. 250.05KB
PYC RP11 Clinical Trial Dosing Completed in Cohort 4
16/05/24PRICE SENSITIVE download Created with Sketch. 480.02KB
PYC Successful GLP Tox Studies in Second Blinding Eye Disease
14/05/24PRICE SENSITIVE download Created with Sketch. 378.74KB
PYC Q2 2024 Investor Webinar Presentation
09/05/24 download Created with Sketch. 726.44KB
PYC Presentation of RP11 Clinical Trial Data at ARVO Conference
06/05/24PRICE SENSITIVE download Created with Sketch. 1.4MB
PYC Ceasing to be a substantial holder
01/05/24 download Created with Sketch. 89.23KB
PYC Q2 Investor Webinar 9 May 2024
01/05/24 download Created with Sketch. 220.33KB
PYC Application for quotation of securities - PYC
30/04/24 download Created with Sketch. 15.49KB
PYC RP11 Drug Candidate Progressing to Mid-Stage Human Trials
29/04/24PRICE SENSITIVE download Created with Sketch. 281.37KB
PYC Quarterly Activities/Appendix 4C Cash Flow Report
26/04/24PRICE SENSITIVE download Created with Sketch. 375.34KB
PYC Kidney Disease Drug Candidate Progressing to Human Trials
22/04/24PRICE SENSITIVE download Created with Sketch. 280.51KB
PYC Change in substantial holding
17/04/24 download Created with Sketch. 193.75KB
PYC Update - Application for quotation of securities - PYC
15/04/24 download Created with Sketch. 15.66KB
PYC Application for quotation of securities - PYC
12/04/24 download Created with Sketch. 14.27KB
PYC Change in substantial holding
11/04/24 download Created with Sketch. 101.29KB
PYC $74.6 Million Extension of Cash Runway
10/04/24PRICE SENSITIVE download Created with Sketch. 248.55KB
PYC Notification of cessation of securities - PYC
03/04/24 download Created with Sketch. 12.93KB
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