PYC THERAPEUTICS LIMITED - Announcements

6.43%

$1.33

Market Cap $772.8M

Healthcare Biotechnology

PYC Therapeutics Limited is an Australia-based clinical-stage biotechnology company... PYC Therapeutics Limited is an Australia-based clinical-stage biotechnology company creating a new generation of ribonucleic acid (RNA) therapies to change the lives of patients with genetic diseases. The Company utilizes its proprietary drug delivery platform to enhance the potency of precision medicines within the rapidly growing and commercially proven RNA therapeutic class. Its drug development programs target monogenic diseases - the indications with the highest likelihood of success in clinical development. Its first-in-class drug programs include Retinitis Pigmentosa type 11, (VP-001), Polycystic Kidney Disease, (PYC-003), Autosomal Dominant Optic Atrophy (ADOA) (PYC-001) and Phelan-McDermid Syndrome (PMS) (PYC-002). The Company's VP-001 program is a lead asset for a blinding eye disease of childhood progressed through multiple patient cohorts in the ongoing single ascending dose clinical trial. ADOA is a progressive and blinding eye disease.More

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Announcements

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PYC	Kidney Disease Drug Candidate Progressing to Human Trials	PRICE SENSITIVE	22/04/24	280.51KB	Share
PYC	Change in substantial holding		17/04/24	193.75KB	Share
PYC	Update - Application for quotation of securities - PYC		15/04/24	15.66KB	Share
PYC	Application for quotation of securities - PYC		12/04/24	14.27KB	Share
PYC	Change in substantial holding		11/04/24	101.29KB	Share
PYC	$74.6 Million Extension of Cash Runway	PRICE SENSITIVE	10/04/24	248.55KB	Share
PYC	Notification of cessation of securities - PYC		03/04/24	12.93KB	Share
PYC	Change of Director's Interest Notice		28/03/24	224.9KB	Share
PYC	Change in substantial holding		28/03/24	194.57KB	Share
PYC	Notification of cessation of securities - PYC		26/03/24	12.88KB	Share
PYC	Application for quotation of securities - PYC		25/03/24	14.32KB	Share
PYC	Despatch of Notice to Ineligible Retail Shareholders		20/03/24	451.48KB	Share
PYC	Despatch of Retail Offer Document		20/03/24	213.71KB	Share
PYC	Retail Entitlement Offer Booklet	PRICE SENSITIVE	20/03/24	2.09MB	Share
PYC	Completion of Institutional Entitlement Offer	PRICE SENSITIVE	18/03/24	235.44KB	Share
PYC	Amended Appendix 3B		15/03/24	205.93KB	Share
PYC	Update - Proposed issue of securities - PYC		15/03/24	18.85KB	Share
PYC	Cleansing Notice Under Section 708AA		14/03/24	296.84KB	Share
PYC	Proposed issue of securities - PYC		14/03/24	18.97KB	Share
PYC	PYC Equity Raising Presentation	PRICE SENSITIVE	14/03/24	1.52MB	Share
PYC	PYC Equity Raising to Raise up to $74.6 Million	PRICE SENSITIVE	14/03/24	269.81KB	Share
PYC	Trading Halt	PRICE SENSITIVE	14/03/24	284.75KB	Share
PYC	Half Yearly Report and Accounts	PRICE SENSITIVE	29/02/24	796.58KB	Share
PYC	RP11 Clinical Trial - Dosing Completed in Cohort 3	PRICE SENSITIVE	28/02/24	348.64KB	Share
PYC	Change of Registered Office		26/02/24	184.99KB	Share
PYC	Receipt of $4.5m Collaboration Fee	PRICE SENSITIVE	16/02/24	144.77KB	Share
PYC	Euroz Hartleys Healthcare Conference Presentation		06/02/24	1.75MB	Share
PYC	Q1 2024 Investor Webinar Presentation		02/02/24	1.69MB	Share
PYC	Quarterly Activities/Appendix 4C Cash Flow Report	PRICE SENSITIVE	25/01/24	367.07KB	Share
PYC	Q1 Investor Call 2 February 2024		22/01/24	196.43KB	Share
PYC	Change of Director's Interest Notice		10/01/24	338.58KB	Share
PYC	AI Driven Drug Discovery Collaboration with Google Cloud	PRICE SENSITIVE	02/01/24	176.79KB	Share
PYC	RP11 Clinical Trial Progressing To High Dose Cohort	PRICE SENSITIVE	18/12/23	257.68KB	Share
PYC	Notification of cessation of securities - PYC		01/12/23	21.66KB	Share
PYC	Response to Price Query	PRICE SENSITIVE	30/11/23	305.03KB	Share
PYC	Results of Annual General Meeting		24/11/23	188.35KB	Share
PYC	2023 AGM Chairman's Address and CEO Presentation		24/11/23	1.25MB	Share
PYC	Annual General Meeting - Conference Call		21/11/23	188.83KB	Share
PYC	Polycystic Kidney Disease Program Presentation		17/11/23	2.47MB	Share
PYC	Supplementary Information	PRICE SENSITIVE	16/11/23	519.24KB	Share
PYC	New Drug For Major Kidney Disease Effective In Human Models	PRICE SENSITIVE	13/11/23	510.34KB	Share
PYC	PYC and FDA Align On Clinical Trial Pathway in ADOA	PRICE SENSITIVE	06/11/23	229.61KB	Share
PYC	RP11 Clinical Trial Dosing Completed In Patient Cohort 2	PRICE SENSITIVE	03/11/23	263.51KB	Share
PYC	Wilsons Drug & Device Conference Presentation		26/10/23	2.35MB	Share
PYC	Quarterly Activities/Appendix 4C Cash Flow Report	PRICE SENSITIVE	25/10/23	378.78KB	Share
PYC	Notice of Annual General Meeting/Proxy Form		24/10/23	866.97KB	Share
PYC	2023 Corporate Governance Statement and Appendix 4G		24/10/23	762.59KB	Share
PYC	Annual Report to shareholders		24/10/23	4.1MB	Share
PYC	PYC Presenting on PYC-001 Program at OTS 2023 Meeting		20/10/23	222.1KB	Share
PYC	Notification regarding unquoted securities - PYC		16/10/23	28.57KB	Share
PYC	Investor Presentation ADOA Program		05/10/23	1.52MB	Share
PYC	PYC-001 Effective In Both NHPs and Patient-Derived Models	PRICE SENSITIVE	04/10/23	463.16KB	Share
PYC	Q3 Investor Call Presentation		27/09/23	596.74KB	Share
PYC	Safety Review Committee Approves Dose Escalation	PRICE SENSITIVE	22/09/23	244.54KB	Share
PYC	Q3 Investor Call 27 September 2023		19/09/23	203.32KB	Share
PYC	E&P Healthcare Conference Presentation		12/09/23	1.94MB	Share
PYC	Appendix 4E and Audited Financial Statements	PRICE SENSITIVE	31/08/23	2.11MB	Share
PYC	Notification of cessation of securities - PYC		21/08/23	21.75KB	Share
PYC	RP11 Clinical Trial Dosing Completed In Patient Cohort 1	PRICE SENSITIVE	17/08/23	222.48KB	Share
PYC	PYC Increases Ownership of VP-001 Program	PRICE SENSITIVE	10/08/23	226.93KB	Share
PYC	PYC Receives FDA Fast Track Designation	PRICE SENSITIVE	02/08/23	228.66KB	Share
PYC	Quarterly Activities/Appendix 4C Cash Flow Report	PRICE SENSITIVE	26/07/23	372.56KB	Share
PYC	Change in substantial holding		18/07/23	114.65KB	Share
PYC	Successful Toxicology Results Pave Way for Phase 2 Trial	PRICE SENSITIVE	18/07/23	263.82KB	Share
PYC	Change in substantial holding		14/07/23	115.71KB	Share
PYC	Change of Director's Interest Notice		14/07/23	209.24KB	Share
PYC	Change of Director's Interest Notice		14/07/23	215.74KB	Share
PYC	Cleansing Notice Under Section 708AA		14/07/23	204.87KB	Share
PYC	Application for quotation of securities - PYC		14/07/23	24.78KB	Share
PYC	Q3 Investor Call Advance Notice		10/07/23	246.81KB	Share
PYC	Results of Meeting		05/07/23	206.94KB	Share
PYC	Change of Director's Interest Notice		04/07/23	224.96KB	Share
PYC	FIRST PATIENT DOSED IN EYE DISEASE CLINICAL TRIAL	PRICE SENSITIVE	30/06/23	252.93KB	Share
PYC	Change of Director's Interest Notice		28/06/23	232.8KB	Share
PYC	PYC Investor Update Presentation		16/06/23	1.42MB	Share
PYC	Q2 Investor Call 16 June 2023		08/06/23	293.56KB	Share
PYC	Phelan-McDermid Syndrome & CNS platform presentation		06/06/23	751.61KB	Share
PYC	Notice of General Meeting/Proxy Form		02/06/23	790.1KB	Share
PYC	Appointment of Joint Company Secretary		01/06/23	177.8KB	Share
PYC	Ceasing to be a substantial holder		22/05/23	96.36KB	Share
PYC	Ceasing to be a substantial holder		22/05/23	272.37KB	Share
PYC	Cleansing Notice Under Section 708AA		19/05/23	204.84KB	Share
PYC	Application for quotation of securities - PYC		19/05/23	24.92KB	Share
PYC	Proposed issue of securities - PYC		11/05/23	25.52KB	Share
PYC	Placement Supporting Document	PRICE SENSITIVE	11/05/23	1.34MB	Share
PYC	Successful Completion of $30m Placement	PRICE SENSITIVE	11/05/23	244.21KB	Share
PYC	Trading Halt	PRICE SENSITIVE	09/05/23	596.74KB	Share
PYC	PYC Presenting at TIDES USA 2023		02/05/23	238.26KB	Share
PYC	Quarterly Activities/Appendix 4C Cash Flow Report	PRICE SENSITIVE	28/04/23	403.56KB	Share
PYC	Commencement of First Clinical Study in RP11	PRICE SENSITIVE	26/04/23	249.84KB	Share
PYC	PYC BIO 2023 Presentation		19/04/23	1.59MB	Share
PYC	Second Drug Program Progressing to Human Trials	PRICE SENSITIVE	03/04/23	358.21KB	Share
PYC	Cleansing Notice Under Section 708AA		07/03/23	244.28KB	Share
PYC	Application for quotation of securities - PYC		07/03/23	29.58KB	Share
PYC	FDA Clears PYC to Commence First Human Trials in RP11	PRICE SENSITIVE	06/03/23	177.28KB	Share
PYC	Trading Halt	PRICE SENSITIVE	02/03/23	570.58KB	Share
PYC	Half Yearly Report and Accounts	PRICE SENSITIVE	28/02/23	1.02MB	Share
PYC	PYC Investor Update Presentation		17/02/23	836.84KB	Share
PYC	Issue of Options		15/02/23	238.22KB	Share
PYC	Notification regarding unquoted securities - PYC		15/02/23	27.94KB	Share

PYC Kidney Disease Drug Candidate Progressing to Human Trials
22/04/24	PRICE SENSITIVE	280.51KB	Share
PYC Change in substantial holding
17/04/24		193.75KB	Share
PYC Update - Application for quotation of securities - PYC
15/04/24		15.66KB	Share
PYC Application for quotation of securities - PYC
12/04/24		14.27KB	Share
PYC Change in substantial holding
11/04/24		101.29KB	Share
PYC $74.6 Million Extension of Cash Runway
10/04/24	PRICE SENSITIVE	248.55KB	Share
PYC Notification of cessation of securities - PYC
03/04/24		12.93KB	Share
PYC Change of Director's Interest Notice
28/03/24		224.9KB	Share
PYC Change in substantial holding
28/03/24		194.57KB	Share
PYC Notification of cessation of securities - PYC
26/03/24		12.88KB	Share
PYC Application for quotation of securities - PYC
25/03/24		14.32KB	Share
PYC Despatch of Notice to Ineligible Retail Shareholders
20/03/24		451.48KB	Share
PYC Despatch of Retail Offer Document
20/03/24		213.71KB	Share
PYC Retail Entitlement Offer Booklet
20/03/24	PRICE SENSITIVE	2.09MB	Share
PYC Completion of Institutional Entitlement Offer
18/03/24	PRICE SENSITIVE	235.44KB	Share
PYC Amended Appendix 3B
15/03/24		205.93KB	Share
PYC Update - Proposed issue of securities - PYC
15/03/24		18.85KB	Share
PYC Cleansing Notice Under Section 708AA
14/03/24		296.84KB	Share
PYC Proposed issue of securities - PYC
14/03/24		18.97KB	Share
PYC PYC Equity Raising Presentation
14/03/24	PRICE SENSITIVE	1.52MB	Share
PYC PYC Equity Raising to Raise up to $74.6 Million
14/03/24	PRICE SENSITIVE	269.81KB	Share
PYC Trading Halt
14/03/24	PRICE SENSITIVE	284.75KB	Share
PYC Half Yearly Report and Accounts
29/02/24	PRICE SENSITIVE	796.58KB	Share
PYC RP11 Clinical Trial - Dosing Completed in Cohort 3
28/02/24	PRICE SENSITIVE	348.64KB	Share
PYC Change of Registered Office
26/02/24		184.99KB	Share
PYC Receipt of $4.5m Collaboration Fee
16/02/24	PRICE SENSITIVE	144.77KB	Share
PYC Euroz Hartleys Healthcare Conference Presentation
06/02/24		1.75MB	Share
PYC Q1 2024 Investor Webinar Presentation
02/02/24		1.69MB	Share
PYC Quarterly Activities/Appendix 4C Cash Flow Report
25/01/24	PRICE SENSITIVE	367.07KB	Share
PYC Q1 Investor Call 2 February 2024
22/01/24		196.43KB	Share
PYC Change of Director's Interest Notice
10/01/24		338.58KB	Share
PYC AI Driven Drug Discovery Collaboration with Google Cloud
02/01/24	PRICE SENSITIVE	176.79KB	Share
PYC RP11 Clinical Trial Progressing To High Dose Cohort
18/12/23	PRICE SENSITIVE	257.68KB	Share
PYC Notification of cessation of securities - PYC
01/12/23		21.66KB	Share
PYC Response to Price Query
30/11/23	PRICE SENSITIVE	305.03KB	Share
PYC Results of Annual General Meeting
24/11/23		188.35KB	Share
PYC 2023 AGM Chairman's Address and CEO Presentation
24/11/23		1.25MB	Share
PYC Annual General Meeting - Conference Call
21/11/23		188.83KB	Share
PYC Polycystic Kidney Disease Program Presentation
17/11/23		2.47MB	Share
PYC Supplementary Information
16/11/23	PRICE SENSITIVE	519.24KB	Share
PYC New Drug For Major Kidney Disease Effective In Human Models
13/11/23	PRICE SENSITIVE	510.34KB	Share
PYC PYC and FDA Align On Clinical Trial Pathway in ADOA
06/11/23	PRICE SENSITIVE	229.61KB	Share
PYC RP11 Clinical Trial Dosing Completed In Patient Cohort 2
03/11/23	PRICE SENSITIVE	263.51KB	Share
PYC Wilsons Drug & Device Conference Presentation
26/10/23		2.35MB	Share
PYC Quarterly Activities/Appendix 4C Cash Flow Report
25/10/23	PRICE SENSITIVE	378.78KB	Share
PYC Notice of Annual General Meeting/Proxy Form
24/10/23		866.97KB	Share
PYC 2023 Corporate Governance Statement and Appendix 4G
24/10/23		762.59KB	Share
PYC Annual Report to shareholders
24/10/23		4.1MB	Share
PYC PYC Presenting on PYC-001 Program at OTS 2023 Meeting
20/10/23		222.1KB	Share
PYC Notification regarding unquoted securities - PYC
16/10/23		28.57KB	Share
PYC Investor Presentation ADOA Program
05/10/23		1.52MB	Share
PYC PYC-001 Effective In Both NHPs and Patient-Derived Models
04/10/23	PRICE SENSITIVE	463.16KB	Share
PYC Q3 Investor Call Presentation
27/09/23		596.74KB	Share
PYC Safety Review Committee Approves Dose Escalation
22/09/23	PRICE SENSITIVE	244.54KB	Share
PYC Q3 Investor Call 27 September 2023
19/09/23		203.32KB	Share
PYC E&P Healthcare Conference Presentation
12/09/23		1.94MB	Share
PYC Appendix 4E and Audited Financial Statements
31/08/23	PRICE SENSITIVE	2.11MB	Share
PYC Notification of cessation of securities - PYC
21/08/23		21.75KB	Share
PYC RP11 Clinical Trial Dosing Completed In Patient Cohort 1
17/08/23	PRICE SENSITIVE	222.48KB	Share
PYC PYC Increases Ownership of VP-001 Program
10/08/23	PRICE SENSITIVE	226.93KB	Share
PYC PYC Receives FDA Fast Track Designation
02/08/23	PRICE SENSITIVE	228.66KB	Share
PYC Quarterly Activities/Appendix 4C Cash Flow Report
26/07/23	PRICE SENSITIVE	372.56KB	Share
PYC Change in substantial holding
18/07/23		114.65KB	Share
PYC Successful Toxicology Results Pave Way for Phase 2 Trial
18/07/23	PRICE SENSITIVE	263.82KB	Share
PYC Change in substantial holding
14/07/23		115.71KB	Share
PYC Change of Director's Interest Notice
14/07/23		209.24KB	Share
PYC Change of Director's Interest Notice
14/07/23		215.74KB	Share
PYC Cleansing Notice Under Section 708AA
14/07/23		204.87KB	Share
PYC Application for quotation of securities - PYC
14/07/23		24.78KB	Share
PYC Q3 Investor Call Advance Notice
10/07/23		246.81KB	Share
PYC Results of Meeting
05/07/23		206.94KB	Share
PYC Change of Director's Interest Notice
04/07/23		224.96KB	Share
PYC FIRST PATIENT DOSED IN EYE DISEASE CLINICAL TRIAL
30/06/23	PRICE SENSITIVE	252.93KB	Share
PYC Change of Director's Interest Notice
28/06/23		232.8KB	Share
PYC PYC Investor Update Presentation
16/06/23		1.42MB	Share
PYC Q2 Investor Call 16 June 2023
08/06/23		293.56KB	Share
PYC Phelan-McDermid Syndrome & CNS platform presentation
06/06/23		751.61KB	Share
PYC Notice of General Meeting/Proxy Form
02/06/23		790.1KB	Share
PYC Appointment of Joint Company Secretary
01/06/23		177.8KB	Share
PYC Ceasing to be a substantial holder
22/05/23		96.36KB	Share
PYC Ceasing to be a substantial holder
22/05/23		272.37KB	Share
PYC Cleansing Notice Under Section 708AA
19/05/23		204.84KB	Share
PYC Application for quotation of securities - PYC
19/05/23		24.92KB	Share
PYC Proposed issue of securities - PYC
11/05/23		25.52KB	Share
PYC Placement Supporting Document
11/05/23	PRICE SENSITIVE	1.34MB	Share
PYC Successful Completion of $30m Placement
11/05/23	PRICE SENSITIVE	244.21KB	Share
PYC Trading Halt
09/05/23	PRICE SENSITIVE	596.74KB	Share
PYC PYC Presenting at TIDES USA 2023
02/05/23		238.26KB	Share
PYC Quarterly Activities/Appendix 4C Cash Flow Report
28/04/23	PRICE SENSITIVE	403.56KB	Share
PYC Commencement of First Clinical Study in RP11
26/04/23	PRICE SENSITIVE	249.84KB	Share
PYC PYC BIO 2023 Presentation
19/04/23		1.59MB	Share
PYC Second Drug Program Progressing to Human Trials
03/04/23	PRICE SENSITIVE	358.21KB	Share
PYC Cleansing Notice Under Section 708AA
07/03/23		244.28KB	Share
PYC Application for quotation of securities - PYC
07/03/23		29.58KB	Share
PYC FDA Clears PYC to Commence First Human Trials in RP11
06/03/23	PRICE SENSITIVE	177.28KB	Share
PYC Trading Halt
02/03/23	PRICE SENSITIVE	570.58KB	Share
PYC Half Yearly Report and Accounts
28/02/23	PRICE SENSITIVE	1.02MB	Share
PYC PYC Investor Update Presentation
17/02/23		836.84KB	Share
PYC Issue of Options
15/02/23		238.22KB	Share
PYC Notification regarding unquoted securities - PYC
15/02/23		27.94KB	Share

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(20min delay)
Last $1.33		Change 0.080(6.43%)		Mkt cap ! $772.8M

Open	High	Low	Value	Volume
$1.27	$1.35	$1.21	$763.8K	595.4K

Buyers (Bids)

No.	Vol.	Price($)
2	97719	$1.30

Sellers (Offers)

Price($)	Vol.	No.
$1.33	6599	1

View Market Depth

No.	Vol.	Price($)
2	97719	1.300
1	4027	1.240
1	40000	1.220
1	1000	1.200
2	10830	1.190

Price($)	Vol.	No.
1.325	6599	1
1.395	7168	1
1.400	18450	1
1.420	26097	2
1.430	13000	1

Last trade - 16.10pm 08/08/2025 (20 minute delay)

PYC (ASX) Chart

PYC THERAPEUTICS LIMITED - Announcements

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